Mir381 MGI Mouse Gene Detail - MGI:3619391

Symbol

Mir381
Name

microRNA 381
Synonyms

mir 381, Mirn381, mmu-mir-381

Feature Type

miRNA gene
IDs

MGI:3619391
NCBI Gene: 723935
Member of

Mirc6 cluster, Mirc36 cluster
Alliance

gene page

Sequence Map

Chr12:109693256-109693330 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 12, 60.56 cM
Mapping Data

1 experiment

SNPs within 2kb

79 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619391	miRNA gene	Chr12:109693256-109693330 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008002	miRNA gene	Chr12:111970468-111970542 (+)
A/J	MGP_AJ_G0007996	miRNA gene	Chr12:107652695-107652769 (+)
AKR/J	MGP_AKRJ_G0007973	miRNA gene	Chr12:110790184-110790258 (+)
BALB/cJ	MGP_BALBcJ_G0007975	miRNA gene	Chr12:108123492-108123566 (+)
C3H/HeJ	MGP_C3HHeJ_G0007921	miRNA gene	Chr12:111233366-111233440 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008156	miRNA gene	Chr12:115381069-115381143 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007283	miRNA gene	Chr12:104172724-104172798 (+)
CAST/EiJ	MGP_CASTEiJ_G0007809	miRNA gene	Chr12:106193002-106193076 (+)
CBA/J	MGP_CBAJ_G0007891	miRNA gene	Chr12:119916112-119916186 (+)
DBA/2J	MGP_DBA2J_G0007926	miRNA gene	Chr12:107207355-107207429 (+)
FVB/NJ	MGP_FVBNJ_G0007945	miRNA gene	Chr12:106001317-106001391 (+)
LP/J	MGP_LPJ_G0008007	miRNA gene	Chr12:111793390-111793464 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007916	miRNA gene	Chr12:123077799-123077873 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008151	miRNA gene	Chr12:110273569-110273643 (+)
PWK/PhJ	MGP_PWKPhJ_G0007731	miRNA gene	Chr12:101817941-101818015 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007628	miRNA gene	Chr12:104438172-104438246 (+)
WSB/EiJ	MGP_WSBEiJ_G0007878	miRNA gene	Chr12:111189138-111189212 (+)

Human Ortholog

MIR381, microRNA 381

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR381, microRNA 381
Synonyms

hsa-mir-381, mir-381, MIRN381
Links

HGNC:31874

NCBI Gene ID: 494330
Chr Location

chr14:101045920-101045994 (+) GRCh38

MGI Vertebrate Homology

Mir381 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR381
Gene Tree

Mir381

Diseases

1 with human MIR381 associations

				Human Disease	Mouse Models
				lung non-small cell carcinoma IDs lung non-small cell carcinoma DOID:3908 EFO:0003060 KEGG:05223 MESH:D002289 NCI:C2926 UMLS_CUI:C0007131

Click on a disease name to see all genes associated with that disease.

less

Phenotype Summary

7 phenotype references

All Mutations and Alleles

4
Targeted

4
Genomic Mutations

3 involving Mir381
Find Mice (IMSR)

1 strains or lines available

less

All GO Annotations

5
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

1
Literature Summary

5

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

less

All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000098838 (Evidence)
NCBI Gene

723935

Representative Sequences				Length	Strain/Species	Flank
	genomic	723935	NCBI Gene Model \| MGI Sequence Detail	75	C57BL/6J	± kb
	transcript	NR_029882	RefSeq \| MGI Sequence Detail	75	C57BL/6

less

All nucleic 2

Other 2

less

miRBase

MI0000798

Summaries

All 22

Developmental Gene Expression 5

Gene Ontology 4

Phenotypes 7
Earliest

J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
Latest

J:346630 Zhang X, et al., Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24