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Mir485 Gene Detail
Summary
  • Symbol
    Mir485
  • Name
    microRNA 485
  • Synonyms
    mir 485, Mirn485, mmu-mir-485
Location &
Maps
more
  • Sequence Map
    Chr12:109701336-109701408 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    86 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3619422
 miRNA gene Chr12:109701336-109701408 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008011
 miRNA gene Chr12:111978548-111978620 (+)
A/J MGP_AJ_G0008005
 miRNA gene Chr12:107660784-107660856 (+)
AKR/J MGP_AKRJ_G0007982
 miRNA gene Chr12:110798264-110798336 (+)
BALB/cJ MGP_BALBcJ_G0007984
 miRNA gene Chr12:108131570-108131642 (+)
C3H/HeJ MGP_C3HHeJ_G0007930
 miRNA gene Chr12:111241456-111241528 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008165
 miRNA gene Chr12:115389207-115389279 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007292
 miRNA gene Chr12:104180858-104180930 (+)
CAST/EiJ MGP_CASTEiJ_G0007818
 miRNA gene Chr12:106201117-106201189 (+)
CBA/J MGP_CBAJ_G0007900
 miRNA gene Chr12:119924206-119924278 (+)
DBA/2J MGP_DBA2J_G0007935
 miRNA gene Chr12:107215417-107215489 (+)
FVB/NJ MGP_FVBNJ_G0007954
 miRNA gene Chr12:106009397-106009469 (+)
LP/J MGP_LPJ_G0008016
 miRNA gene Chr12:111801470-111801542 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007925
 miRNA gene Chr12:123085909-123085981 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008160
 miRNA gene Chr12:110281649-110281721 (+)
PWK/PhJ MGP_PWKPhJ_G0007740
 miRNA gene Chr12:101826102-101826174 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007637
 miRNA gene Chr12:104446272-104446344 (+)
WSB/EiJ MGP_WSBEiJ_G0007887
 miRNA gene Chr12:111197238-111197310 (+)



Homology
more
  • Human Ortholog
    MIR485, microRNA 485
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR485, microRNA 485
  • Synonyms
    hsa-mir-485, mir-485, MIRN485
  • Links
    NCBI Gene ID: 574436

  • Chr Location
    chr14:101055419-101055491 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit fewer, larger brown fat cell, insulin resistance, and impaired glucose tolerance whether fed standard chow or a high-fat diet under cold conditions.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    846
  • Tissues
    18
  • Literature Summary
    3
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723875 NCBI Gene Model | MGI Sequence Detail 73 C57BL/6J ±  kb
transcript NR_030253 RefSeq | MGI Sequence Detail 73 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    Other 2
Other Database
Links
less
miRBase MI0003492
References
more
  • Summaries
    All 16
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:338912 Jones BT, et al., Target-directed microRNA degradation regulates developmental microRNA expression and embryonic growth in mammals. Genes Dev. 2023 Aug 8;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory