Mir9-3 MGI Mouse Gene Detail - MGI:3619443

Symbol

Mir9-3
Name

microRNA 9-3
Synonyms

mir 9-3, Mirn9-3, mmu-mir-9-3

Feature Type

miRNA gene
IDs

MGI:3619443
NCBI Gene: 723968
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr7:79155012-79155101 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 45.06 cM
Mapping Data

1 experiment

SNPs within 2kb

40 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3619443	miRNA gene	Chr7:79155012-79155101 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0009039	miRNA gene	Chr7:81391754-81391843 (+)
A/J	MGP_AJ_G0009022	miRNA gene	Chr7:79514369-79514458 (+)
AKR/J	MGP_AKRJ_G0009011	miRNA gene	Chr7:81217583-81217672 (+)
BALB/cJ	MGP_BALBcJ_G0009008	miRNA gene	Chr7:79209911-79210000 (+)
C3H/HeJ	MGP_C3HHeJ_G0008946	miRNA gene	Chr7:81881167-81881256 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0009247	miRNA gene	Chr7:84593463-84593552 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0008128	miRNA gene	Chr7:82055733-82055822 (+)
CAST/EiJ	MGP_CASTEiJ_G0008783	miRNA gene	Chr7:72751650-72751739 (+)
CBA/J	MGP_CBAJ_G0008917	miRNA gene	Chr7:87423903-87423992 (+)
DBA/2J	MGP_DBA2J_G0008945	miRNA gene	Chr7:78089314-78089403 (+)
FVB/NJ	MGP_FVBNJ_G0008965	miRNA gene	Chr7:78001937-78002026 (+)
LP/J	MGP_LPJ_G0009042	miRNA gene	Chr7:82642237-82642326 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008930	miRNA gene	Chr7:87610080-87610169 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0009216	miRNA gene	Chr7:80671509-80671598 (+)
PWK/PhJ	MGP_PWKPhJ_G0008712	miRNA gene	Chr7:71255272-71255361 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0008553	miRNA gene	Chr7:67656603-67656692 (+)
WSB/EiJ	MGP_WSBEiJ_G0008878	miRNA gene	Chr7:80994683-80994772 (+)

Human Ortholog

MIR9-3, microRNA 9-3

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR9-3, microRNA 9-3
Synonyms

hsa-mir-9-3, mir-9-3, MIRN9-3, miRNA9-3
Links

HGNC:31646

NCBI Gene ID: 407051
Chr Location

chr15:89368017-89368106 (+) GRCh38

MGI Vertebrate Homology

Mir9-3 stringent orthology
1 human;1 mouse;1 zebrafish
HCOP

vertebrate homology predictions: MIR9-3
Gene Tree

Mir9-3

Diseases

1 with human MIR9-3 associations

				Human Disease	Mouse Models
				lung squamous cell carcinoma IDs lung squamous cell carcinoma DOID:3907 NCI:C3493 UMLS_CUI:C0149782

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
23 phenotypes from multigenic genotypes
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

5
Chemically induced (other)

1
Radiation induced

2
Targeted

2
Genomic Mutations

3 involving Mir9-3
Find Mice (IMSR)

2 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Male and female mice homozygous for a null mutation are infertile.

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All GO Annotations

10
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

841
Tissues

64
Literature Summary

30

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

GEO

Expression Atlas

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All Sequences

25
RefSeq

1

Ensembl

ENSMUSG00000093238 (Evidence)
NCBI Gene

723968

Representative Sequences				Length	Strain/Species	Flank
	genomic	723968	NCBI Gene Model \| MGI Sequence Detail	90	C57BL/6J	± kb
	transcript	NR_029818	RefSeq \| MGI Sequence Detail	90	C57BL/6

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All nucleic 19

Genomic 1

Primer pair 8

Other 10

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miRBase

MI0000721

Summaries

All 60

Developmental Gene Expression 30

Gene Ontology 6

Phenotypes 13
Earliest

J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
Latest

J:356218 Szakats S, et al., Sex-biased gene and microRNA expression in the developing mouse brain is associated with neurodevelopmental functions and neurological phenotypes. Biol Sex Differ. 2023 Sep 7;14(1):57

TSS for Mir9-3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr67353	Chr7:79154689-79154702 (+)	-316 bp
Tssr67354	Chr7:79155084-79155095 (+)	78 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24