Ts(16C-tel)1Cje Cytogenetic Marker Detail

Summary

• Symbol
  Ts(16C-tel)1Cje
• Name
  trisomy, (16C-tel), 1 Charles J Epstein
• Synonyms
  partial trisomy 16, Ts108Cje, Ts(12¹⁶)1Cje, Ts1Cje

• Feature Type
  unclassified cytogenetic marker
• IDs
  MGI:3623021

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 16, Syntenic

Human Diseases

• Diseases
  1 with Ts(16C-tel)1Cje mouse models

Human Disease

Mouse Models

Down syndrome

IDs

Down syndrome      

DOID:14250
ICD10CM:Q90
ICD9CM:758.0
MESH:D004314
NCI:C2993
OMIM:190685
ORDO:870
UMLS_CUI:C0013080

View 3 models

Mouse Models

Human Disease Modeled: Down syndrome

Allelic Composition	Genetic Background	Reference	Phenotypes
Ts(16C-tel)1Cje/0	B6.Cg-Ts(16C-tel)1Cje	J:294908	View
Ts(16C-tel)1Cje/0	involves: C3H/HeSnJ * C57BL/6J * CD-1 * Rb(16.17)32Lub * STOCK Rb(11.16)2H/H	J:47907	View
Ts(16C-tel)1Cje/0	involves: C57BL/6J * Rb(11.16)2H * Rb(16.17)32Lub	J:174270 J:241597	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  4 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  28 phenotypes from 1 allele in 5 genetic backgrounds
  5 phenotypes from multigenic genotypes
  58 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 59

  Diseases 4

  Phenotypes 58
• Earliest
  J:42265 Huang TT, et al., Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts. Arch Biochem Biophys. 1997 Aug 15;344(2):424-32
• Latest
  J:325522 Urbano-Gamez JD, et al., Prenatal treatment with rapamycin restores enhanced hippocampal mGluR-LTD and mushroom spine size in a Down's syndrome mouse model. Mol Brain. 2021 May 25;14(1):84