Mir181a-1 MGI Mouse Gene Detail - MGI:3629589

Symbol

Mir181a-1
Name

microRNA 181a-1
Synonyms

mir 181a-1, miR-213, Mirn181a-1, Mirn213, mmu-mir-181a-1, mmu-mir-213

Feature Type

miRNA gene
IDs

MGI:3629589
NCBI Gene: 735252
Member of

Mirc14 cluster
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:137894193-137894279 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 60.68 cM
Mapping Data

1 experiment

SNPs within 2kb

134 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3629589	miRNA gene	Chr1:137894193-137894279 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0007663	miRNA gene	Chr1:141968328-141968414 (+)
A/J	MGP_AJ_G0007658	miRNA gene	Chr1:136480060-136480146 (+)
AKR/J	MGP_AKRJ_G0007632	miRNA gene	Chr1:140576060-140576146 (+)
BALB/cJ	MGP_BALBcJ_G0007636	miRNA gene	Chr1:136812753-136812839 (+)
C3H/HeJ	MGP_C3HHeJ_G0007581	miRNA gene	Chr1:140676468-140676554 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0007811	miRNA gene	Chr1:146957602-146957688 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0006975	miRNA gene	Chr1:129534509-129534595 (+)
CAST/EiJ	MGP_CASTEiJ_G0007477	miRNA gene	Chr1:139832762-139832848 (+)
CBA/J	MGP_CBAJ_G0007556	miRNA gene	Chr1:152026285-152026371 (+)
DBA/2J	MGP_DBA2J_G0007590	miRNA gene	Chr1:135463267-135463353 (+)
FVB/NJ	MGP_FVBNJ_G0007604	miRNA gene	Chr1:134118933-134119019 (+)
LP/J	MGP_LPJ_G0007669	miRNA gene	Chr1:143076796-143076882 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0007578	miRNA gene	Chr1:157687604-157687690 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0007811	miRNA gene	Chr1:140346123-140346209 (+)
PWK/PhJ	MGP_PWKPhJ_G0007410	miRNA gene	Chr1:134550953-134551039 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0007312	miRNA gene	Chr1:139330716-139330802 (+)
WSB/EiJ	MGP_WSBEiJ_G0007545	miRNA gene	Chr1:140377607-140377693 (+)

Human Ortholog

MIR181A1, microRNA 181a-1

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MIR181A1, microRNA 181a-1
Synonyms

hsa-mir-181a-1, mir-181a-1, mir-213, MIR213, MIRN181A1, MIRN213
Links

HGNC:31590

NCBI Gene ID: 406995
Chr Location

chr1:198859044-198859153 (-) GRCh38

MGI Vertebrate Homology

Mir181a-1 stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: MIR181A1
Gene Tree

Mir181a-1

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

3
Chemically induced (other)

2
Radiation induced

1
Genomic Mutations

3 involving Mir181a-1
Find Mice (IMSR)

1 strains or lines available

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All GO Annotations

4
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

727
Tissues

11
Literature Summary

14

Images

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

24
RefSeq

1

Ensembl

ENSMUSG00000065565 (Evidence)
NCBI Gene

735252

Representative Sequences				Length	Strain/Species	Flank
	genomic	735252	NCBI Gene Model \| MGI Sequence Detail	87	C57BL/6J	± kb
	transcript	NR_029795	RefSeq \| MGI Sequence Detail	87	C57BL/6

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All nucleic 5

Primer pair 3

Other 2

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miRBase

MI0000697

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MGI:2676889

Summaries

All 45

Developmental Gene Expression 14

Gene Ontology 4

Phenotypes 4
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:340964 Jimenez MT, et al., The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium. J Exp Med. 2022 Dec 5;219(12)

TSS for Mir181a-1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr9131	Chr1:137893162-137893180 (+)	-1,022 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24