About   Help   FAQ
Gm15441 Gene Detail
Summary
  • Symbol
    Gm15441
  • Name
    predicted gene 15441
  • Synonyms
    ENSMUSG00000074398
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3641753
    NCBI Gene: 100038464
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96463084-96474117 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    328 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3641753
 lncRNA gene Chr3:96463071-96474117 (-)
129S1/SvImJ MGP_129S1SvImJ_G0003795
 antisense lncRNA gene Chr3:97431552-97445808 (-)
A/J MGP_AJ_G0003776
 antisense lncRNA gene Chr3:94318124-94329169 (-)
AKR/J MGP_AKRJ_G0003752
 antisense lncRNA gene Chr3:96538728-96549758 (-)
BALB/cJ MGP_BALBcJ_G0003763
 antisense lncRNA gene Chr3:94129965-94140980 (-)
C3H/HeJ MGP_C3HHeJ_G0003710
 antisense lncRNA gene Chr3:96841211-96852232 (-)
C57BL/6NJ MGP_C57BL6NJ_G0003904
 antisense lncRNA gene Chr3:100985870-100998140 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0003408
 antisense lncRNA gene Chr3:90600131-90610890 (-)
CAST/EiJ MGP_CASTEiJ_G0003674
 antisense lncRNA gene Chr3:96098113-96110091 (-)
CBA/J MGP_CBAJ_G0003705
 antisense lncRNA gene Chr3:104679183-104692008 (-)
DBA/2J MGP_DBA2J_G0003716
 antisense lncRNA gene Chr3:93651027-93662096 (-)
FVB/NJ MGP_FVBNJ_G0003737
 antisense lncRNA gene Chr3:91661321-91672780 (-)
LP/J MGP_LPJ_G0003797
 antisense lncRNA gene Chr3:98719894-98730706 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0003724
 antisense lncRNA gene Chr3:110755836-110766843 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0003905
 antisense lncRNA gene Chr3:96156192-96167922 (-)
PWK/PhJ MGP_PWKPhJ_G0003630
 antisense lncRNA gene Chr3:93483836-93495121 (-)
SPRET/EiJ MGP_SPRETEiJ_G0003574
 antisense lncRNA gene Chr3:94458281-94469325 (-)
WSB/EiJ MGP_WSBEiJ_G0003710
 antisense lncRNA gene Chr3:96607380-96618376 (-)



Homology
less
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout leads to upregulation, after fasting, of the inflammasome pathway and increases lipid accumulation in the liver after fasting.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      31
    • RefSeq
      1
    • UniProt
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100038464 NCBI Gene Model | MGI Sequence Detail 11034 C57BL/6J ±  kb
    transcript NR_040409 RefSeq | MGI Sequence Detail 1673 C57BL/6  
    polypeptide Q3UPP6 UniProt | EBI | MGI Sequence Detail 68 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    References
    more
    • Summaries
      All 20
      Diseases 1
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:299830 Brocker CN, et al., Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting. Nat Commun. 2020 Nov 17;11(1):5847
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory