Krtap12-23 MGI Mouse Gene Detail - MGI:3642183 - keratin associated protein 12-23

Symbol

Krtap12-23
Name

keratin associated protein 12-23
Synonyms

Gm10272

Feature Type

protein coding gene
IDs

MGI:3642183
NCBI Gene: 16697
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr10:77542460-77542809 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 39.72 cM
Mapping Data

1 experiment

SNPs within 2kb

117 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3642183	protein coding gene	Chr10:77542423-77542820 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017403	protein coding gene	Chr10:78051751-78052083 (+)
A/J	MGP_AJ_G0017379	protein coding gene	Chr10:75331368-75331700 (+)
AKR/J	MGP_AKRJ_G0017341	protein coding gene	Chr10:77341207-77341539 (+)
BALB/cJ	MGP_BALBcJ_G0017340	protein coding gene	Chr10:75525262-75525594 (+)
C3H/HeJ	MGP_C3HHeJ_G0017164	protein coding gene	Chr10:77424860-77425192 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017798	protein coding gene	Chr10:80800929-80801261 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015487	protein coding gene	Chr10:71762738-71763100 (+)
CAST/EiJ	MGP_CASTEiJ_G0016734	protein coding gene	Chr10:77788535-77788897 (+)
CBA/J	MGP_CBAJ_G0017136	protein coding gene	Chr10:83899876-83900208 (+)
DBA/2J	MGP_DBA2J_G0017241	protein coding gene	Chr10:74606855-74607187 (+)
FVB/NJ	MGP_FVBNJ_G0017233	protein coding gene	Chr10:73784026-73784358 (+)
LP/J	MGP_LPJ_G0017314	protein coding gene	Chr10:78512682-78513014 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017262	protein coding gene	Chr10:85935996-85936328 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017837	protein coding gene	Chr10:77430930-77431262 (+)
PWK/PhJ	MGP_PWKPhJ_G0016517	protein coding gene	Chr10:74490504-74490827 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016301	protein coding gene	Chr10:76683539-76683901 (+)
WSB/EiJ	MGP_WSBEiJ_G0016796	protein coding gene	Chr10:77403942-77404274 (+)

Human Ortholog

KRTAP12-1, keratin associated protein 12-1

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

KRTAP12-1, keratin associated protein 12-1
Synonyms

KAP12.1, KRTAP12.1
Links

HGNC:20529

NCBI Gene ID: 353332

neXtProt AC: NX_P59990

UniProt: P59990
Chr Location

21q22.3; chr21:44681576-44682163 (-) GRCh38

Human Ortholog

KRTAP12-2, keratin associated protein 12-2
Synonyms

KAP12.2, KRTAP12.2
Links

HGNC:20530

NCBI Gene ID: 353323

neXtProt AC: NX_P59991

UniProt: P59991
Chr Location

21q22.3; chr21:44666189-44666927 (-) GRCh38

Human Ortholog

KRTAP12-3, keratin associated protein 12-3
Synonyms

KRTAP12.3
Links

HGNC:20531

NCBI Gene ID: 386683

neXtProt AC: NX_P60328

UniProt: P60328
Chr Location

21q22.3; chr21:44657932-44658341 (+) GRCh38

MGI Vertebrate Homology

Krtap12-23 stringent orthology
3 human;1 mouse;2 rat
HCOP

vertebrate homology predictions: KRTAP12-1, KRTAP12-2, KRTAP12-3
Gene Tree

Krtap12-23

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References

2 with disease annotations

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Phenotype Summary

28 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

1
Targeted

3
Genomic Mutations

4 involving Krtap12-23
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

6 strains or lines available

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All GO Annotations

1
GO References

1

Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

1

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

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All Sequences

26
RefSeq

2
UniProt

1

Ensembl

ENSMUSG00000069584 (Evidence)
NCBI Gene

16697

			Length	Strain/Species	Flank
genomic	ENSMUSG00000069584	Ensembl Gene Model \| MGI Sequence Detail	350	C57BL/6J	± kb
transcript	ENSMUST00000092371	Ensembl \| MGI Sequence Detail	350	Not Applicable
polypeptide	ENSMUSP00000090025	Ensembl \| MGI Sequence Detail	110	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR002494 Keratin-associated protein

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All nucleic 1

cDNA 1

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MGI:7580937

Summaries

All 37

Diseases 2

Gene Ontology 1

Phenotypes 28
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:351211 Wu Y, et al., Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathol Commun. 2023 Aug 14;11(1):132

TSS for Krtap12-23:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr94281	Chr10:77542422-77542425 (+)	-36 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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