Fbxw22 Gene Detail

Summary

• Symbol
  Fbxw22
• Name
  F-box and WD-40 domain protein 22
• Synonyms
  Gm5164

• Feature Type
  protein coding gene
• IDs
  MGI:3643290
  NCBI Gene: 382156
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr9:109207468-109233362 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, 59.65 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  639 from dbSNP Build 142
• Strain Annotations
  4

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3643290	protein coding gene	Chr9:109207468-109233364 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	MGP_BALBcJ_G0035307	protein coding gene	Chr9:107033101-107206277 (-)
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0035825	protein coding gene	Chr9:114396612-114437390 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0035130	protein coding gene	Chr9:119909873-120409166 (-)
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  FBXW12, F-box and WD repeat domain containing 12
  
• Synonyms
  FBW12, FBXO12, FBXO35
• Links
  HGNC:20729

  NCBI Gene ID: 285231

  neXtProt AC: NX_Q6X9E4

  UniProt: Q6X9E4

  
  
• Chr Location
  3p21.31; chr3:48372219-48401259 (+)  GRCh38

---

• MGI Vertebrate Homology
  Fbxw22 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: FBXW12
• Gene Tree
  Fbxw22
  

Mutations,
Alleles, and
Phenotypes

• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  30 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  8

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  28
• RefSeq
  11
• UniProt
  3
• CCDS
  CCDS40772.1

• Ensembl
  ENSMUSG00000070324 (Evidence)
• NCBI Gene
  382156

Representative Sequences			Length	Strain/Species
genomic	382156	NCBI Gene Model | MGI Sequence Detail	25895	C57BL/6J
transcript	NM_001014395	RefSeq | MGI Sequence Detail	1827	C57BL/6
polypeptide	NP_001014417	RefSeq | MGI Sequence Detail	466	C57BL/6

Protein
Information

• UniProt
  3 Sequences
• InterPro Domains
  IPR001810 F-box domain
  IPR036047 F-box-like domain superfamily
  IPR052121 F-box Protein Family Substrate Recognition Components
  IPR036322 WD40-repeat-containing domain superfamily
  IPR015943 WD40/YVTN repeat-like-containing domain superfamily

Molecular
Reagents

• All nucleic 8

  cDNA 8

  
  

  Microarray probesets 1

References

• Summaries
  All 11

  Gene Ontology 1
• Earliest
  J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
• Latest
  J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;