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Bhmt1b Gene Detail
Summary
  • Symbol
    Bhmt1b
  • Name
    betaine--homocysteine S-methyltransferase 1B
  • Synonyms
    Gm5096
Location &
Maps
more
  • Sequence Map
    Chr18:87774410-87776275 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 58.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3643681
 protein coding gene Chr18:87774410-87776278 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028106
 protein coding gene Chr4:23501774-23502638 (-)
A/J MGP_AJ_G0028064
 protein coding gene Chr4:22825895-22827451 (-)
AKR/J MGP_AKRJ_G0020753
 protein coding gene Chr13:94228187-94238761 (-)
BALB/cJ MGP_BALBcJ_G0020776
 protein coding gene Chr13:92081600-92088014 (-)
C3H/HeJ MGP_C3HHeJ_G0027805
 protein coding gene Chr4:23518647-23520581 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025027
 protein coding gene Chr18:91331811-91333629 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0027921
 protein coding gene Chr4:22747532-22751836 (-)
FVB/NJ MGP_FVBNJ_G0020635
 protein coding gene Chr13:90016772-90031996 (-)
LP/J MGP_LPJ_G0020727
 protein coding gene Chr13:95096952-95109976 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0023373
 protein coding gene Chr18:87939209-87940556 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    BHMT, betaine--homocysteine S-methyltransferase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BHMT, betaine--homocysteine S-methyltransferase
  • Synonyms
    BHMT1, HEL-S-61p
  • Links
    NCBI Gene ID: 635
    neXtProt AC: NX_Q93088
    UniProt: Q93088

  • Chr Location
    5q14.1; chr5:79111809-79132288 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human BHMT associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    16
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069324 Ensembl Gene Model | MGI Sequence Detail 1866 C57BL/6J ±  kb
transcript ENSMUST00000091776 Ensembl | MGI Sequence Detail 1866 Not Applicable  
polypeptide ENSMUSP00000135956 Ensembl | MGI Sequence Detail 407 Not Applicable  
For the selected sequence
Other
Accession IDs
less
MGI:7280676
References
more
  • Summaries
    All 7
    Gene Ontology 2
  • Earliest
    J:62863 Neece DJ, et al., Isolation and characterization of a mouse betaine-homocysteine S-methyltransferase gene and pseudogene. Gene. 2000 May 30;250(1-2):31-40
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory