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Eif4a3l1 Gene Detail
Summary
  • Symbol
    Eif4a3l1
  • Name
    eukaryotic translation initiation factor 4A3 like 1
  • Synonyms
    B020013A22Rik, Gm8994
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644226
    NCBI Gene: 668137
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:136304537-136306981 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 66.54 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    238 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644226
 protein coding gene Chr6:136304537-136306981 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030892
 protein coding gene Chr6:79037970-79038607 (+)
A/J MGP_AJ_G0030861
 protein coding gene Chr6:75960055-75962001 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0031403
 protein coding gene Chr6:135024328-135025032 (+)
C3H/HeJ MGP_C3HHeJ_G0030839
 protein coding gene Chr6:106083410-106084324 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031331
 protein coding gene Chr6:81141489-81146907 (+)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0030711
 protein coding gene Chr6:75332147-75333427 (+)
FVB/NJ MGP_FVBNJ_G0030664
 protein coding gene Chr6:74597517-74599193 (+)
LP/J MGP_LPJ_G0019381
 protein coding gene Chr11:123983320-123990316 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030700
 protein coding gene Chr6:88345429-88346968 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031637
 protein coding gene Chr6:117766793-117767666 (+)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    EIF4A3, eukaryotic translation initiation factor 4A3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EIF4A3, eukaryotic translation initiation factor 4A3
  • Synonyms
    DDX48, eIF-4A-III, eIF4A-III, eIF4AIII, Fal1, MUK34, NMP265, NUK34, RCPS
  • Links
    NCBI Gene ID: 9775
    neXtProt AC: NX_P38919
    UniProt: P38919

  • Chr Location
    17q25.3; chr17:80134369-80147151 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human EIF4A3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 668137 NCBI Gene Model | MGI Sequence Detail 2445 C57BL/6J ±  kb
transcript NM_001142734 RefSeq | MGI Sequence Detail 1573 C57BL/6  
polypeptide NP_001136206 RefSeq | MGI Sequence Detail 411 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • EC
    3.6.4.13
  • InterPro Domains
    IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
    IPR011545 DEAD/DEAH box helicase domain
    IPR001650 Helicase, C-terminal domain-like
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR014014 RNA helicase, DEAD-box type, Q motif
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 1
Other
Accession IDs
less
MGI:3809663, MGI:6330775
References
more
  • Summaries
    All 13
    Gene Ontology 3
  • Earliest
    J:23000 MGD Nomenclature Committee, Nomenclature Committee Use. 1995-02-14;
  • Latest
    J:57747 MGI Genome Annotation Group and UniGene Staff, MGI-UniGene Interconnection Effort. Database Download. 2015;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory