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Sgo2b Gene Detail
Summary
  • Symbol
    Sgo2b
  • Name
    shugoshin 2B
  • Synonyms
    Gm4975, Sgol2b
  • Feature Type
    protein coding gene
  • IDs
    MGI:3644562
    NCBI Gene: 244495
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr8:64377728-64405204 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 32.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1319 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3644562
 protein coding gene Chr8:64360461-64405204 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033640
 protein coding gene Chr8:63909270-63943353 (-)
A/J MGP_AJ_G0033622
 protein coding gene Chr8:61201807-61230056 (-)
AKR/J MGP_AKRJ_G0033547
 protein coding gene Chr8:62953950-62978550 (-)
BALB/cJ MGP_BALBcJ_G0033618
 protein coding gene Chr8:61483406-61508810 (-)
C3H/HeJ MGP_C3HHeJ_G0033328
 protein coding gene Chr8:63667099-63690468 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034135
 protein coding gene Chr8:66294757-66326388 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014157
 protein coding gene Chr1:51762158-51783445 (+)
CAST/EiJ MGP_CASTEiJ_G0032653
 protein coding gene Chr8:63118037-63145677 (-)
CBA/J MGP_CBAJ_G0033306
 protein coding gene Chr8:68762382-68786386 (-)
DBA/2J MGP_DBA2J_G0033460
 protein coding gene Chr8:60965836-60989516 (-)
FVB/NJ MGP_FVBNJ_G0033401
 protein coding gene Chr8:60246035-60273450 (-)
LP/J MGP_LPJ_G0033548
 protein coding gene Chr8:63922627-63955040 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033445
 protein coding gene Chr8:71258933-71289498 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034153
 protein coding gene Chr8:63233882-63262863 (-)
PWK/PhJ MGP_PWKPhJ_G0032362
 protein coding gene Chr8:60348611-60375837 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032198
 protein coding gene Chr8:62196126-62225401 (-)
WSB/EiJ MGP_WSBEiJ_G0032770
 protein coding gene Chr8:63612014-63639444 (-)



Homology
more
  • Human Ortholog
    SGO2, shugoshin 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SGO2, shugoshin 2
  • Synonyms
    SGOL2, TRIPIN
  • Links
    NCBI Gene ID: 151246
    neXtProt AC: NX_Q562F6
    UniProt: Q562F6

  • Chr Location
    2q33.1; chr2:200510008-200584096 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Genomic Mutations
    1 involving Sgo2b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    34 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 244495 NCBI Gene Model | MGI Sequence Detail 27477 C57BL/6J ±  kb
transcript NM_001195687 RefSeq | MGI Sequence Detail 3739 C57BL/6  
polypeptide NP_001182616 RefSeq | MGI Sequence Detail 1167 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR038889 Shugoshin 1/2
  • GlyGen
    J3QMK1 3 sites, 3 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 1
Other
Accession IDs
less
MGI:5892221
References
more
  • Summaries
    All 15
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory