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Nhsl2 Gene Detail
Summary
  • Symbol
    Nhsl2
  • Name
    NHS like 2
  • Synonyms
    1110062M06Rik, Gm10456
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645090
    NCBI Gene: 100042480
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:100892991-101135661 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 44.75 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4379 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645090
 protein coding gene ChrX:100892942-101135661 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035967
 protein coding gene ChrX:98402326-98658783 (+)
A/J MGP_AJ_G0035952
 protein coding gene ChrX:98377186-98625235 (+)
AKR/J MGP_AKRJ_G0035868
 protein coding gene ChrX:101221355-101475561 (+)
BALB/cJ MGP_BALBcJ_G0035935
 protein coding gene ChrX:97123411-97365412 (+)
C3H/HeJ MGP_C3HHeJ_G0035644
 protein coding gene ChrX:98796389-99046598 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036465
 protein coding gene ChrX:101320401-101569505 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033294
 protein coding gene ChrX:96095115-96339333 (+)
CAST/EiJ MGP_CASTEiJ_G0034931
 protein coding gene ChrX:83093997-83350289 (+)
CBA/J MGP_CBAJ_G0035619
 protein coding gene ChrX:104471181-104734426 (+)
DBA/2J MGP_DBA2J_G0035773
 protein coding gene ChrX:97596266-97841627 (+)
FVB/NJ MGP_FVBNJ_G0035712
 protein coding gene ChrX:96966934-97210774 (+)
LP/J MGP_LPJ_G0035864
 protein coding gene ChrX:99337527-99588266 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035746
 protein coding gene ChrX:108996863-109264706 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036491
 protein coding gene ChrX:98070413-98316548 (+)
PWK/PhJ MGP_PWKPhJ_G0034630
 protein coding gene ChrX:80691437-80935374 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034458
 protein coding gene ChrX:84016996-84262354 (+)
WSB/EiJ MGP_WSBEiJ_G0035070
 protein coding gene ChrX:96770081-97021502 (+)



Homology
more
  • Human Ortholog
    NHSL2, NHS like 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    35
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000079481 Ensembl Gene Model | MGI Sequence Detail 242671 C57BL/6J ±  kb
    transcript ENSMUST00000101339 Ensembl | MGI Sequence Detail 12971 Not Applicable  
    polypeptide ENSMUSP00000098893 Ensembl | MGI Sequence Detail 1219 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000011206 NHS-like protein 2
      (term hierarchy)
    • InterPro Domains
      IPR024845 Actin remodeling regulator NHS-like
    • GlyGen
      B1AXH1 3 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 35
      cDNA 35

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1916100, MGI:2147854, MGI:2148011, MGI:3642348
    References
    more
    • Summaries
      All 28
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory