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Calhm3 Gene Detail
Summary
  • Symbol
    Calhm3
  • Name
    calcium homeostasis modulator 3
Location &
Maps
more
  • Sequence Map
    Chr19:47140138-47146203 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 39.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    366 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645665
 protein coding gene Chr19:47140048-47146203 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025226
 protein coding gene Chr19:46930138-46937177 (-)
A/J MGP_AJ_G0025202
 protein coding gene Chr19:44587450-44593352 (-)
AKR/J MGP_AKRJ_G0025171
 protein coding gene Chr19:46047577-46054695 (-)
BALB/cJ MGP_BALBcJ_G0025197
 protein coding gene Chr19:44644984-44650851 (-)
C3H/HeJ MGP_C3HHeJ_G0024957
 protein coding gene Chr19:46227058-46232919 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025640
 protein coding gene Chr19:48050306-48056359 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023053
 protein coding gene Chr19:43831597-43837649 (-)
CAST/EiJ MGP_CASTEiJ_G0024422
 protein coding gene Chr19:46039898-46045951 (-)
CBA/J MGP_CBAJ_G0024937
 protein coding gene Chr19:50491669-50497553 (-)
DBA/2J MGP_DBA2J_G0025069
 protein coding gene Chr19:44403302-44409191 (-)
FVB/NJ MGP_FVBNJ_G0025030
 protein coding gene Chr19:44195683-44202145 (-)
LP/J MGP_LPJ_G0025155
 protein coding gene Chr19:46825821-46831652 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025061
 protein coding gene Chr19:49782530-49788426 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025698
 protein coding gene Chr19:46168692-46174589 (-)
PWK/PhJ MGP_PWKPhJ_G0024171
 protein coding gene Chr19:44366331-44372859 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023974
 protein coding gene Chr19:44824212-44830304 (-)
WSB/EiJ MGP_WSBEiJ_G0024492
 protein coding gene Chr19:46314336-46320615 (-)



Homology
more
  • Human Ortholog
    CALHM3, calcium homeostasis modulator 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALHM3, calcium homeostasis modulator 3
  • Synonyms
    bA225H22.7, FAM26A
  • Links
    NCBI Gene ID: 119395
    neXtProt AC: NX_Q86XJ0
    UniProt: Q86XJ0

  • Chr Location
    10q24.33; chr10:103472804-103479240 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit impaired voltage-activated nonselective currents, avoidance of bitter and salty taste, and loss of preference for sweet and unami.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    2
  • cDNA Data
    1
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      25
    • RefSeq
      1
    • UniProt
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 240669 NCBI Gene Model | MGI Sequence Detail 6066 C57BL/6J ±  kb
    polypeptide J3QMI4 UniProt | EBI | MGI Sequence Detail 347 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 1
      Primer pair 1
    References
    more
    • Summaries
      All 17
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 2
    • Earliest
      J:244828 Wu J, et al., Generation of Calhm1 knockout mouse and characterization of calhm1 gene expression. Protein Cell. 2012 Jun;3(6):470-80
    • Latest
      J:335201 Ohmoto M, et al., A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells. eNeuro. 2023 Apr;10(4):ENEURO.0236-22.2023
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory