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Gng14 Gene Detail
Summary
  • Symbol
    Gng14
  • Name
    G protein subunit gamma 14
  • Synonyms
    Gm5741
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645690
    NCBI Gene: 100503710
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr8:85794197-85794611 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    103 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645690
protein coding gene Chr8:85794141-85794647 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033891
protein coding gene Chr8:86014220-86014634 (-)
A/J MGP_AJ_G0033874
protein coding gene Chr8:82615998-82616412 (-)
AKR/J MGP_AKRJ_G0033800
protein coding gene Chr8:85073087-85073501 (-)
BALB/cJ MGP_BALBcJ_G0033867
protein coding gene Chr8:82751451-82751865 (-)
C3H/HeJ MGP_C3HHeJ_G0033577
protein coding gene Chr8:85691752-85692166 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034387
protein coding gene Chr8:89305576-89305990 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031328
protein coding gene Chr8:76419182-76419577 (-)
CAST/EiJ MGP_CASTEiJ_G0032907
protein coding gene Chr8:85122821-85123235 (-)
CBA/J MGP_CBAJ_G0033553
protein coding gene Chr8:92336355-92336769 (-)
DBA/2J MGP_DBA2J_G0033706
protein coding gene Chr8:82254587-82255001 (-)
FVB/NJ MGP_FVBNJ_G0033654
protein coding gene Chr8:81213839-81214253 (-)
LP/J MGP_LPJ_G0033798
protein coding gene Chr8:86119002-86119416 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033696
protein coding gene Chr8:94897857-94898271 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034404
protein coding gene Chr8:85061744-85062158 (-)
PWK/PhJ MGP_PWKPhJ_G0032610
protein coding gene Chr8:81501645-81502059 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032447
protein coding gene Chr8:83881600-83882014 (-)
WSB/EiJ MGP_WSBEiJ_G0033020
protein coding gene Chr8:85489136-85489550 (-)



Homology
more
  • Human Ortholog
    GNG14, G protein subunit gamma 14
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GNG14, G protein subunit gamma 14
  • Synonyms
    HG3K
  • Links
    NCBI Gene ID: 105372280
    UniProt: A0A1W2PPG7

  • Chr Location
    chr19:12687998-12688422 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    34 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Gng14
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000095845 Ensembl Gene Model | MGI Sequence Detail 415 C57BL/6J ±  kb
transcript ENSMUST00000177563 Ensembl | MGI Sequence Detail 328 Not Applicable  
polypeptide ENSMUSP00000136655 Ensembl | MGI Sequence Detail 72 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR015898 G-protein gamma-like domain
    IPR036284 G-protein gamma-like domain superfamily
    IPR001770 G-protein, gamma subunit
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2
Other
Accession IDs
less
MGI:7284406
References
more
  • Summaries
    All 42
    Gene Ontology 1
    Phenotypes 34
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory