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Krtap27-1 Gene Detail
Summary
  • Symbol
    Krtap27-1
  • Name
    keratin associated protein 27-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646229
    NCBI Gene: 239933
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:88467914-88468559 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 51.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646229
 protein coding gene Chr16:88467914-88468612 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022988
 protein coding gene Chr16:89483903-89484548 (-)
A/J MGP_AJ_G0022956
 protein coding gene Chr16:85331655-85332300 (-)
AKR/J MGP_AKRJ_G0022926
 protein coding gene Chr16:87920848-87921493 (-)
BALB/cJ MGP_BALBcJ_G0022958
 protein coding gene Chr16:85861520-85862165 (-)
C3H/HeJ MGP_C3HHeJ_G0022720
 protein coding gene Chr16:88493553-88494198 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023405
 protein coding gene Chr16:92352782-92353427 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020909
 protein coding gene Chr16:83162257-83162902 (-)
CAST/EiJ MGP_CASTEiJ_G0022242
 protein coding gene Chr16:88924331-88924973 (-)
CBA/J MGP_CBAJ_G0022689
 protein coding gene Chr16:96321118-96321763 (-)
DBA/2J MGP_DBA2J_G0022823
 protein coding gene Chr16:85263899-85264544 (-)
FVB/NJ MGP_FVBNJ_G0022798
 protein coding gene Chr16:84358903-84359548 (-)
LP/J MGP_LPJ_G0022892
 protein coding gene Chr16:89164086-89164731 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022817
 protein coding gene Chr16:100847913-100848558 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023423
 protein coding gene Chr16:88424174-88424819 (-)
PWK/PhJ MGP_PWKPhJ_G0021985
 protein coding gene Chr16:85414882-85415527 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021815
 protein coding gene Chr16:87974544-87975186 (-)
WSB/EiJ MGP_WSBEiJ_G0022290
 protein coding gene Chr16:88642404-88643049 (-)



Homology
more
  • Human Ortholog
    KRTAP27-1, keratin associated protein 27-1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP27-1, keratin associated protein 27-1
  • Links
    NCBI Gene ID: 643812
    neXtProt AC: NX_Q3LI81
    UniProt: Q3LI81

  • Chr Location
    21q22.11; chr21:30337013-30337694 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000090515 Ensembl Gene Model | MGI Sequence Detail 646 C57BL/6J ±  kb
transcript ENSMUST00000165580 Ensembl | MGI Sequence Detail 646 Not Applicable  
polypeptide ENSMUSP00000129289 Ensembl | MGI Sequence Detail 202 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007951 Keratin-associated protein, PMG type
    IPR007659 Keratin, high-sulphur matrix protein
References
more
  • Summaries
    All 14
    Phenotypes 6
  • Earliest
    J:117029 Davisson M, et al., Impact of trisomy on fertility and meiosis in male mice. Hum Reprod. 2007 Feb;22(2):468-76
  • Latest
    J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory