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Gm5478 Gene Detail
Summary
  • Symbol
    Gm5478
  • Name
    predicted pseudogene 5478
Location &
Maps
more
  • Sequence Map
    Chr15:101551455-101555815 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.95 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    214 from dbSNP Build 142
  • Strain Annotations
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646318
 protein coding gene Chr15:101551454-101555815 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0022796
 protein coding gene Chr15:107615319-107623426 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J MGP_DBA2J_G0022213
 protein coding gene Chr15:98977774-99016434 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    KRT6A, keratin 6A
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRT6A, keratin 6A
  • Synonyms
    CK6A, CK-6C, CK6C, CK6D, CK-6E, K6A, K6C, K6D, KRT6C, KRT6D, PC3
  • Links
    NCBI Gene ID: 3853
    neXtProt AC: NX_P02538
    UniProt: P02538

  • Chr Location
    12q13.13; chr12:52487176-52493257 (-)  GRCh38
  • Human Ortholog
    KRT6B, keratin 6B
  • Synonyms
    CK-6B, CK6B, K6B, KRTL1, PC2, PC4
  • Links
    NCBI Gene ID: 3854
    neXtProt AC: NX_P04259
    UniProt: P04259

  • Chr Location
    12q13.13; chr12:52446651-52452146 (-)  GRCh38
  • Human Ortholog
    KRT6C, keratin 6C
  • Synonyms
    K6E, KRT6E, PPKNEFD
  • Links
    NCBI Gene ID: 286887
    neXtProt AC: NX_P48668
    UniProt: P48668

  • Chr Location
    12q13.13; chr12:52468516-52473805 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human KRT6A,KRT6B,KRT6C associations

Human Disease Mouse Models
      
IDs
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    4 involving Gm5478
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    11 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
Sequences &
Gene Models
less
  • All Sequences
    15
  • RefSeq
    2
  • UniProt
    2
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000095241 Ensembl Gene Model | MGI Sequence Detail 4361 C57BL/6J ±  kb
transcript ENSMUST00000229963 Ensembl | MGI Sequence Detail 2158 Not Applicable  
polypeptide ENSMUSP00000155269 Ensembl | MGI Sequence Detail 535 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less
  • All nucleic 2
    cDNA 2

    Microarray probesets 1
References
more
  • Summaries
    All 36
    Diseases 1
    Gene Ontology 1
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory