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Trim5 Gene Detail
Summary
  • Symbol
    Trim5
  • Name
    tripartite motif-containing 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:3646853
    NCBI Gene: 667823
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr7:103912593-103937301 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 55.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    756 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3646853
 protein coding gene Chr7:103912593-103937448 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032713
 protein coding gene Chr7:107487990-107504575 (-)
A/J MGP_AJ_G0032688
 protein coding gene Chr7:104673998-104689743 (-)
AKR/J MGP_AKRJ_G0032621
 protein coding gene Chr7:107299130-107313240 (-)
BALB/cJ MGP_BALBcJ_G0032698
 protein coding gene Chr7:104405926-104422301 (-)
C3H/HeJ MGP_C3HHeJ_G0032409
 protein coding gene Chr7:107553360-107569654 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033192
 protein coding gene Chr7:111555269-111623840 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030188
 protein coding gene Chr7:106765939-106780224 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0032377
 protein coding gene Chr7:115465613-115479973 (-)
DBA/2J MGP_DBA2J_G0032531
 protein coding gene Chr7:103009098-103023915 (-)
FVB/NJ MGP_FVBNJ_G0032484
 protein coding gene Chr7:102718373-102733964 (-)
LP/J MGP_LPJ_G0032624
 protein coding gene Chr7:108816383-108833380 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032516
 protein coding gene Chr7:116942008-116960104 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033221
 protein coding gene Chr7:106482851-106501389 (-)
PWK/PhJ MGP_PWKPhJ_G0031452
 protein coding gene Chr7:96006091-96025537 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031296
 protein coding gene Chr7:93626321-93635690 (-)
WSB/EiJ MGP_WSBEiJ_G0031853
 protein coding gene Chr7:107144827-107163570 (-)



Homology
more
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM5, tripartite motif containing 5
  • Synonyms
    RNF88, TRIM5alpha
  • Links
    NCBI Gene ID: 85363
    neXtProt AC: NX_Q9C035
    UniProt: Q9C035

  • Chr Location
    11p15.4; chr11:5588635-5938619 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    28
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060441 Ensembl Gene Model | MGI Sequence Detail 24709 C57BL/6J ±  kb
transcript ENSMUST00000098179 Ensembl | MGI Sequence Detail 3655 Not Applicable  
polypeptide ENSMUSP00000095781 Ensembl | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 3
    Primer pair 1
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:349812 Schafer A, et al., Mapping of susceptibility loci for Ebola virus pathogenesis in mice. Cell Rep. 2024 May 28;43(5):114127
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory