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Urad Gene Detail
Summary
  • Symbol
    Urad
  • Name
    ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
  • Synonyms
    EG231903, Prhoxnb
  • Feature Type
    protein coding gene
  • IDs
    MGI:3647519
    NCBI Gene: 231903
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:147251794-147259250 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 86.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    292 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3647519
 protein coding gene Chr5:147251794-147259250 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030388
 protein coding gene Chr5:152961771-152969189 (-)
A/J MGP_AJ_G0030361
 protein coding gene Chr5:146484683-146492107 (-)
AKR/J MGP_AKRJ_G0030288
 protein coding gene Chr5:150986683-150993814 (-)
BALB/cJ MGP_BALBcJ_G0030370
 protein coding gene Chr5:147699017-147706433 (-)
C3H/HeJ MGP_C3HHeJ_G0030084
 protein coding gene Chr5:151950677-151958093 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030825
 protein coding gene Chr5:158561971-158569367 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028038
 protein coding gene Chr5:140899661-140907177 (-)
CAST/EiJ MGP_CASTEiJ_G0029486
 protein coding gene Chr5:151512318-151519759 (-)
CBA/J MGP_CBAJ_G0030062
 protein coding gene Chr5:165175928-165200706 (-)
DBA/2J MGP_DBA2J_G0030206
 protein coding gene Chr5:146167864-146175306 (-)
FVB/NJ MGP_FVBNJ_G0030160
 protein coding gene Chr5:145364392-145372383 (-)
LP/J MGP_LPJ_G0030293
 protein coding gene Chr5:153663361-153670769 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030196
 protein coding gene Chr5:167448402-167455810 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030855
 protein coding gene Chr5:150892308-150899719 (-)
PWK/PhJ MGP_PWKPhJ_G0029200
 protein coding gene Chr5:145251548-145263806 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029036
 protein coding gene Chr5:148216681-148225297 (-)
WSB/EiJ MGP_WSBEiJ_G0029563
 protein coding gene Chr5:151696612-151705800 (-)



Homology
more
  • Human Ortholog
    URAD, ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    URAD, ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
  • Synonyms
    PRHOXNB
  • Links
    NCBI Gene ID: 646625
    neXtProt AC: NX_A6NGE7
    UniProt: A6NGE7

  • Chr Location
    13q12.2; chr13:27977717-27988693 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 231903 NCBI Gene Model | MGI Sequence Detail 7457 C57BL/6J ±  kb
transcript NM_001039678 RefSeq | MGI Sequence Detail 786 Not Specified  
polypeptide Q283N4 UniProt | EBI | MGI Sequence Detail 178 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000013535 putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
    (term hierarchy)
  • EC
    4.1.1.97
  • InterPro Domains
    IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1
    IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
    IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 15
    Developmental Gene Expression 1
    Gene Ontology 3
  • Earliest
    J:122989 Visel A, et al., GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
  • Latest
    J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory