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Tstd1 Gene Detail
Summary
  • Symbol
    Tstd1
  • Name
    thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
  • Synonyms
    Gm4848
  • Feature Type
    protein coding gene
  • IDs
    MGI:3648482
    NCBI Gene: 226654
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:171246601-171247920 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 79.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    155 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3648482
 protein coding gene Chr1:171246440-171247920 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016762
 protein coding gene Chr1:177220335-177221815 (+)
A/J MGP_AJ_G0016742
 protein coding gene Chr1:169995565-169997045 (+)
AKR/J MGP_AKRJ_G0016708
 protein coding gene Chr1:175091432-175092912 (+)
BALB/cJ MGP_BALBcJ_G0016703
 protein coding gene Chr1:170490401-170491881 (+)
C3H/HeJ MGP_C3HHeJ_G0016526
 protein coding gene Chr1:175344739-175346219 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017164
 protein coding gene Chr1:183111517-183112997 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014872
 protein coding gene Chr1:161684453-161685959 (+)
CAST/EiJ MGP_CASTEiJ_G0016107
 protein coding gene Chr1:174969129-174970634 (+)
CBA/J MGP_CBAJ_G0016501
 protein coding gene Chr1:189621819-189623299 (+)
DBA/2J MGP_DBA2J_G0016608
 protein coding gene Chr1:168838253-168839733 (+)
FVB/NJ MGP_FVBNJ_G0016604
 protein coding gene Chr1:167190225-167191705 (+)
LP/J MGP_LPJ_G0016679
 protein coding gene Chr1:178330890-178332370 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016631
 protein coding gene Chr1:196897960-196899448 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017201
 protein coding gene Chr1:174959944-174961424 (+)
PWK/PhJ MGP_PWKPhJ_G0015893
 protein coding gene Chr1:168061974-168063454 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015677
 protein coding gene Chr1:173752136-173753656 (+)
WSB/EiJ MGP_WSBEiJ_G0016169
 protein coding gene Chr1:175081095-175082575 (+)



Homology
more
  • Human Ortholog
    TSTD1, thiosulfate sulfurtransferase like domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSTD1, thiosulfate sulfurtransferase like domain containing 1
  • Synonyms
    KAT, TST
  • Links
    NCBI Gene ID: 100131187
    neXtProt AC: NX_Q8NFU3
    UniProt: Q8NFU3

  • Chr Location
    1q23.3; chr1:161037631-161038977 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Targeted
    1
  • Genomic Mutations
    2 involving Tstd1
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 226654 NCBI Gene Model | MGI Sequence Detail 1320 C57BL/6J ±  kb
transcript NM_001164525 RefSeq | MGI Sequence Detail 551 C57BL/6  
polypeptide NP_001157997 RefSeq | MGI Sequence Detail 133 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001763 Rhodanese-like domain
    IPR036873 Rhodanese-like domain superfamily
    IPR042457 Thiosulfate:glutathione sulfurtransferase, mammalian
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:2138518
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory