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Aadacl4 Gene Detail
Summary
  • Symbol
    Aadacl4
  • Name
    arylacetamide deacetylase like 4
  • Synonyms
    Gm13177
  • Feature Type
    protein coding gene
  • IDs
    MGI:3650257
    NCBI Gene: 435815
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:144340277-144349968 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 78.01 cM
Strain
Comparison
more
  • SNPs within 2kb
    273 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3650257
 protein coding gene Chr4:144340277-144349968 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029096
 protein coding gene Chr4:147995386-148004868 (-)
A/J MGP_AJ_G0029063
 protein coding gene Chr4:141710693-141720360 (+)
AKR/J MGP_AKRJ_G0029011
 protein coding gene Chr4:145680049-145689720 (+)
BALB/cJ MGP_BALBcJ_G0029078
 protein coding gene Chr4:142364718-142374399 (+)
C3H/HeJ MGP_C3HHeJ_G0028797
 protein coding gene Chr4:146144030-146153711 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029523
 protein coding gene Chr4:152993308-153002991 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026775
 protein coding gene Chr4:134403806-134413592 (-)
CAST/EiJ MGP_CASTEiJ_G0028213
 protein coding gene Chr4:144223513-144233179 (-)
CBA/J MGP_CBAJ_G0028761
 protein coding gene Chr4:157805711-157815396 (+)
DBA/2J MGP_DBA2J_G0028909
 protein coding gene Chr4:141926271-141935937 (-)
FVB/NJ MGP_FVBNJ_G0028871
 protein coding gene Chr4:141052873-141062532 (+)
LP/J MGP_LPJ_G0029000
 protein coding gene Chr4:148071618-148081098 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028901
 protein coding gene Chr4:161344304-161353983 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029560
 protein coding gene Chr4:146154041-146163725 (+)
PWK/PhJ MGP_PWKPhJ_G0027933
 protein coding gene Chr4:138409674-138419431 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027767
 protein coding gene Chr4:141435107-141444610 (-)
WSB/EiJ MGP_WSBEiJ_G0028292
 protein coding gene Chr4:146412483-146423895 (+)



Homology
more
  • Human Ortholog
    AADACL4, arylacetamide deacetylase like 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AADACL4, arylacetamide deacetylase like 4
  • Links
    NCBI Gene ID: 343066
    neXtProt AC: NX_Q5VUY2
    UniProt: Q5VUY2

  • Chr Location
    1p36.21; chr1:12644085-12667076 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

Biological Process

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 435815 NCBI Gene Model | MGI Sequence Detail 9692 C57BL/6J ±  kb
    transcript NM_001081248 RefSeq | MGI Sequence Detail 1224 Not Specified  
    polypeptide NP_001074717 RefSeq | MGI Sequence Detail 407 Not Specified  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • InterPro Domains
      IPR029058 Alpha/Beta hydrolase fold
      IPR013094 Alpha/beta hydrolase fold-3
      IPR050466 Diverse Carboxylesterases and Gibberellin Receptors
    Molecular
    Reagents
    less
    • All nucleic 3
      cDNA 3

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:5896355
    References
    more
    • Summaries
      All 20
      Phenotypes 8
    • Earliest
      J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
    • Latest
      J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory