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Krtap4-25 Gene Detail
Summary
  • Symbol
    Krtap4-25
  • Name
    keratin associated protein 4-25
  • Synonyms
    2310045F10Rik, Gm11563
  • Feature Type
    protein coding gene
  • IDs
    MGI:3650330
    NCBI Gene: 100040248
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:99548775-99549786 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3650330
 protein coding gene Chr11:99548768-99549786 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019110
 protein coding gene Chr11:102352030-102353041 (-)
A/J MGP_AJ_G0019080
 protein coding gene Chr11:98035673-98036684 (-)
AKR/J MGP_AKRJ_G0019050
 protein coding gene Chr11:101070181-101071192 (-)
BALB/cJ MGP_BALBcJ_G0019052
 protein coding gene Chr11:98540793-98541792 (-)
C3H/HeJ MGP_C3HHeJ_G0018866
 protein coding gene Chr11:101236720-101237731 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019502
 protein coding gene Chr11:105478279-105479290 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017136
 protein coding gene Chr11:95587595-95588671 (-)
CAST/EiJ MGP_CASTEiJ_G0018421
 protein coding gene Chr11:102234175-102235186 (-)
CBA/J MGP_CBAJ_G0018839
 protein coding gene Chr11:109878395-109880112 (-)
DBA/2J MGP_DBA2J_G0018945
 protein coding gene Chr11:97610679-97611690 (-)
FVB/NJ MGP_FVBNJ_G0018936
 protein coding gene Chr11:97103921-97104932 (-)
LP/J MGP_LPJ_G0019016
 protein coding gene Chr11:102836814-102837825 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018963
 protein coding gene Chr11:109537746-109539586 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019544
 protein coding gene Chr11:101441510-101442627 (-)
PWK/PhJ MGP_PWKPhJ_G0018190
 protein coding gene Chr11:98674644-98675886 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0018471
 protein coding gene Chr11:101412239-101413250 (-)



Homology
more
  • Human Ortholog
    KRTAP4-11, keratin associated protein 4-11
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KRTAP4-11, keratin associated protein 4-11
  • Synonyms
    KAP4.11, KAP4.14, KRTAP4-14, KRTAP4.14
  • Links
    NCBI Gene ID: 653240
    neXtProt AC: NX_Q9BYQ6
    UniProt: Q9BYQ6

  • Chr Location
    17q21.2
  • Human Ortholog
    KRTAP4-5, keratin associated protein 4-5
  • Synonyms
    KAP4.5, KRTAP4.5
  • Links
    NCBI Gene ID: 85289
    neXtProt AC: NX_Q9BYR2
    UniProt: Q9BYR2

  • Chr Location
    17q21.2; chr17:41148924-41149825 (-)  GRCh38
  • Human Ortholog
    KRTAP4-8, keratin associated protein 4-8
  • Synonyms
    KAP4.8, KRTAP4.8
  • Links
    NCBI Gene ID: 728224
    neXtProt AC: NX_Q9BYQ9
    UniProt: Q9BYQ9

  • Chr Location
    17q21.2; chr17:41096981-41098142 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069718 Ensembl Gene Model | MGI Sequence Detail 1012 C57BL/6J ±  kb
transcript ENSMUST00000092695 Ensembl | MGI Sequence Detail 1012 Not Applicable  
polypeptide ENSMUSP00000090369 Ensembl | MGI Sequence Detail 168 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR002494 Keratin-associated protein
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 2
Other
Accession IDs
less
MGI:1923720, MGI:7580866
References
more
  • Summaries
    All 23
    Phenotypes 6
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:230728 Kumar V, et al., A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory