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Lncucc1 Gene Detail
Summary
  • Symbol
    Lncucc1
  • Name
    ulcerative colitis circadian clock long noncoding RNA 1
  • Synonyms
    Gm12122, Lnc-UC
  • Feature Type
    lncRNA gene
  • IDs
    MGI:3650741
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:35240896-35241612 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 20.95 cM
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3650741
 lncRNA gene Chr11:35240896-35241612 (+)
129S1/SvImJ MGP_129S1SvImJ_G0036891
 sense intronic lncRNA gene Chr11:33728042-33728758 (+)
A/J MGP_AJ_G0036879
 sense intronic lncRNA gene Chr11:32473630-32474346 (+)
AKR/J MGP_AKRJ_G0036826
 sense intronic lncRNA gene Chr11:33455258-33455974 (+)
BALB/cJ MGP_BALBcJ_G0036870
 sense intronic lncRNA gene Chr11:32637216-32637932 (+)
C3H/HeJ MGP_C3HHeJ_G0036555
 sense intronic lncRNA gene Chr11:33401894-33402610 (+)
C57BL/6NJ MGP_C57BL6NJ_G0037383
 sense intronic lncRNA gene Chr11:34756016-34756732 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0035744
 sense intronic lncRNA gene Chr11:33384396-33385027 (+)
CBA/J MGP_CBAJ_G0036530
 sense intronic lncRNA gene Chr11:36461955-36462671 (+)
DBA/2J MGP_DBA2J_G0036707
 sense intronic lncRNA gene Chr11:32219693-32220409 (+)
FVB/NJ MGP_FVBNJ_G0036658
 sense intronic lncRNA gene Chr11:32061506-32062222 (+)
LP/J MGP_LPJ_G0036753
 sense intronic lncRNA gene Chr11:33954756-33955472 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0036664
 sense intronic lncRNA gene Chr11:37188119-37188805 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0037499
 sense intronic lncRNA gene Chr11:33475175-33475892 (+)
PWK/PhJ MGP_PWKPhJ_G0035438
 sense intronic lncRNA gene Chr11:32300670-32301507 (+)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0035944
 sense intronic lncRNA gene Chr11:33250314-33251030 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele show increased susceptibility to dextran sulfate sodium-induced colitis and loss of diurnal rhythmicity in colitis severity after oxazolone treatment.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      18
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000086311 Ensembl Gene Model | MGI Sequence Detail 717 C57BL/6J ±  kb
    transcript ENSMUST00000124503 Ensembl | MGI Sequence Detail 454 Not Applicable  
    For the selected sequence
    Other
    Accession IDs
    less
    MGI:7541107
    References
    more
    • Summaries
      All 8
      Phenotypes 4
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:340220 Wang S, et al., An NF-kappaB-driven lncRNA orchestrates colitis and circadian clock. Sci Adv. 2020 Oct;6(42)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory