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Timd5 Gene Detail
Summary
  • Symbol
    Timd5
  • Name
    T cell immunoglobulin and mucin domain containing 5
  • Synonyms
    Gm12169
  • Feature Type
    protein coding gene
  • IDs
    MGI:3650838
    NCBI Gene: 210535
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:46415078-46428983 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 27.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    663 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3650838
 protein coding gene Chr11:46415039-46428983 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018196
 protein coding gene Chr11:45444609-45458601 (+)
A/J MGP_AJ_G0018168
 protein coding gene Chr11:43687268-43701321 (+)
AKR/J MGP_AKRJ_G0018134
 protein coding gene Chr11:44961517-44977150 (+)
BALB/cJ MGP_BALBcJ_G0018137
 protein coding gene Chr11:43845841-43859798 (+)
C3H/HeJ MGP_C3HHeJ_G0017951
 protein coding gene Chr11:44991132-45005088 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018591
 protein coding gene Chr11:46785601-46799546 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016246
 protein coding gene Chr11:41665562-41680119 (+)
CAST/EiJ MGP_CASTEiJ_G0017514
 protein coding gene Chr11:45119618-45134439 (+)
CBA/J MGP_CBAJ_G0017923
 protein coding gene Chr11:48976565-48992339 (+)
DBA/2J MGP_DBA2J_G0018033
 protein coding gene Chr11:43432353-43446556 (+)
FVB/NJ MGP_FVBNJ_G0018027
 protein coding gene Chr11:43119288-43133275 (+)
LP/J MGP_LPJ_G0018105
 protein coding gene Chr11:45705173-45720613 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018051
 protein coding gene Chr11:50512425-50527805 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018630
 protein coding gene Chr11:45114376-45128566 (+)
PWK/PhJ MGP_PWKPhJ_G0017294
 protein coding gene Chr11:43527736-43542150 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017087
 protein coding gene Chr11:44934298-44948867 (+)
WSB/EiJ MGP_WSBEiJ_G0017564
 protein coding gene Chr11:44806350-44821536 (+)



Homology
more
  • Human Ortholog
    HAVCR1, hepatitis A virus cellular receptor 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HAVCR1, hepatitis A virus cellular receptor 1
  • Synonyms
    CD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1
  • Links
    NCBI Gene ID: 26762
    neXtProt AC: NX_Q96D42
    UniProt: Q96D42

  • Chr Location
    5q33.3; chr5:157026742-157069407 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human HAVCR1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 210535 NCBI Gene Model | MGI Sequence Detail 13906 C57BL/6J ±  kb
transcript NM_001163357 RefSeq | MGI Sequence Detail 1026 C57BL/6  
polypeptide NP_001156829 RefSeq | MGI Sequence Detail 250 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR003599 Immunoglobulin subtype
    IPR013106 Immunoglobulin V-set domain
    IPR052331 T-cell immunoglobulin and mucin domain-containing protein
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 1
Other
Accession IDs
less
MGI:2144661, MGI:7516777
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory