Gm12610 MGI Mouse Gene Detail - MGI:3652143

Symbol

Gm12610
Name

predicted gene 12610
Synonyms

ANRIL, LncR-APDC, lncRNA APDC

Feature Type

lncRNA gene
IDs

MGI:3652143
NCBI Gene: 102633081
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr4:89213417-89406858 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 42.15 cM

SNPs within 2kb

5637 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3652143	lncRNA gene	Chr4:89213089-89452672 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015556	unclassified non-coding RNA gene	Chr4:89367396-89412119 (+)
A/J	MGP_AJ_G0015533	unclassified non-coding RNA gene	Chr4:86223482-86265655 (+)
AKR/J	MGP_AKRJ_G0015497	unclassified non-coding RNA gene	Chr4:88334294-88376113 (+)
BALB/cJ	MGP_BALBcJ_G0015495	unclassified non-coding RNA gene	Chr4:86452865-86499084 (+)
C3H/HeJ	MGP_C3HHeJ_G0015317	unclassified non-coding RNA gene	Chr4:89096846-89138868 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0015948	unclassified non-coding RNA gene	Chr4:92735950-92782462 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013684	unclassified non-coding RNA gene	Chr4:82118645-82161705 (+)
CAST/EiJ	MGP_CASTEiJ_G0014872	unclassified non-coding RNA gene	Chr4:86934210-86980449 (+)
CBA/J	MGP_CBAJ_G0015298	unclassified non-coding RNA gene	Chr4:95636442-95685566 (+)
DBA/2J	MGP_DBA2J_G0015392	unclassified non-coding RNA gene	Chr4:85967901-86010232 (+)
FVB/NJ	MGP_FVBNJ_G0015399	unclassified non-coding RNA gene	Chr4:84927390-84968901 (+)
LP/J	MGP_LPJ_G0015472	unclassified non-coding RNA gene	Chr4:89641844-89684421 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015422	unclassified non-coding RNA gene	Chr4:100613259-100657049 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0015990	unclassified non-coding RNA gene	Chr4:88514895-88558373 (+)
PWK/PhJ	MGP_PWKPhJ_G0014657	unclassified non-coding RNA gene	Chr4:84266568-84309306 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014446	unclassified non-coding RNA gene	Chr4:86022549-86065690 (+)
WSB/EiJ	MGP_WSBEiJ_G0014977	unclassified non-coding RNA gene	Chr4:88706034-88749722 (+)

less

Gene Tree

Gm12610

less

Phenotype Summary

11 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

2
Radiation induced

1
Targeted

1
Genomic Mutations

4 involving Gm12610
Find Mice (IMSR)

0 strains or lines available

less

All GO Annotations

5
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

2

Tissue x Stage Matrix

Other Mouse Links

Expression Atlas

less

All Sequences

58
RefSeq

1

Ensembl

ENSMUSG00000086035 (Evidence)
NCBI Gene

102633081

Representative Sequences				Length	Strain/Species	Flank
	genomic	102633081	NCBI Gene Model \| MGI Sequence Detail	193442	C57BL/6J	± kb
	transcript	NR_132431	RefSeq \| MGI Sequence Detail	2069	C57BL/6

less

All nucleic 2

cDNA 2

Summaries

All 20

Gene Ontology 1

Phenotypes 11
Earliest

J:158126 Visel A, et al., Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature. 2010 Mar 18;464(7287):409-12
Latest

J:350135 Liu Y, et al., Long non-coding RNA APDC plays important regulatory roles in metabolism of bone and adipose tissues. RNA Biol. 2023 Jan;20(1):836-846

TSS for Gm12610:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr37781	Chr4:89212993-89213006 (+)	-417 bp
Tssr37782	Chr4:89213099-89213140 (+)	-297 bp
Tssr37783	Chr4:89213534-89213544 (+)	122 bp
Tssr37784	Chr4:89221117-89221121 (+)	7,702 bp
Tssr1229	Chr4:89335588-89335589 (+)	122,172 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24