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Ldlrad1 Gene Detail
Summary
  • Symbol
    Ldlrad1
  • Name
    low density lipoprotein receptor class A domain containing 1
  • Synonyms
    OTTMUSG00000008594
  • Feature Type
    protein coding gene
  • IDs
    MGI:3652166
    NCBI Gene: 546840
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:107066377-107075257 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 50.16 cM
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3652166
 protein coding gene Chr4:107066264-107081341 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028534
 protein coding gene Chr4:107884968-107894081 (+)
A/J MGP_AJ_G0028497
 protein coding gene Chr4:104017910-104027758 (+)
AKR/J MGP_AKRJ_G0028444
 protein coding gene Chr4:106562717-106572160 (+)
BALB/cJ MGP_BALBcJ_G0028516
 protein coding gene Chr4:104212874-104221753 (+)
C3H/HeJ MGP_C3HHeJ_G0028230
 protein coding gene Chr4:107314213-107324161 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028956
 protein coding gene Chr4:111763584-111772464 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026247
 protein coding gene Chr4:99296768-99305557 (+)
CAST/EiJ MGP_CASTEiJ_G0027666
 protein coding gene Chr4:105127330-105135995 (+)
CBA/J MGP_CBAJ_G0028199
 protein coding gene Chr4:115387203-115396084 (+)
DBA/2J MGP_DBA2J_G0028347
 protein coding gene Chr4:103639025-103652656 (+)
FVB/NJ MGP_FVBNJ_G0028315
 protein coding gene Chr4:102507162-102519346 (+)
LP/J MGP_LPJ_G0028448
 protein coding gene Chr4:108082592-108091472 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028341
 protein coding gene Chr4:120677337-120687601 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028992
 protein coding gene Chr4:106807714-106816652 (+)
PWK/PhJ MGP_PWKPhJ_G0027392
 protein coding gene Chr4:101883886-101892529 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027216
 protein coding gene Chr4:104200404-104208955 (+)
WSB/EiJ MGP_WSBEiJ_G0027747
 protein coding gene Chr4:106983149-106992786 (+)



Homology
more
  • Human Ortholog
    LDLRAD1, low density lipoprotein receptor class A domain containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LDLRAD1, low density lipoprotein receptor class A domain containing 1
  • Links
    NCBI Gene ID: 388633
    neXtProt AC: NX_Q5T700
    UniProt: Q5T700

  • Chr Location
    1p32.3; chr1:54007298-54018186 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    3
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000070877 Ensembl Gene Model | MGI Sequence Detail 8881 C57BL/6J ±  kb
transcript ENSMUST00000094916 Ensembl | MGI Sequence Detail 1093 Not Applicable  
polypeptide ENSMUSP00000092521 Ensembl | MGI Sequence Detail 218 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR036055 LDL receptor-like superfamily
    IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
    IPR050685 Low-density lipoprotein receptor
Molecular
Reagents
less

  • Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Phenotypes 13
  • Earliest
    J:84714 Nishijima I, et al., Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis. 2003 Jul;36(3):142-8
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory