Tg(TPO-cre)1Shk
Transgene Detail

Summary

• Symbol: Tg(TPO-cre)1Shk
• Name: transgene insertion 1, Shioko Kimura
• MGI ID: MGI:3653644
• Synonyms: TPO-cre
• Transgene: Tg(TPO-cre)1Shk Location: unknown Genetic Position: Chr9, Syntenic
• Alliance: Tg(TPO-cre)1Shk page

Transgene origin

• Strain of Origin: FVB/NCr

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(TPO-cre)1Shk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  TPO (7173)

  Tpo	(MGI:98813)

• Mutation details: This transgene expresses cre recombinase under the control of the human thyroid peroxidase gene promoter. Insulator sequences were placed upstream and downstream of the TPO-cre cassette. The insertion site was found to be between bp 12,372,316 and 12,372,324 on mouse chromosome 9, near Cntn5 and Jrkl, approximately 1.5 and 0.9 Mbp from the transgene, respectively (J:303278). (J:92293)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	TPO (human) Summary of all recombinase alleles driven by TPO. Comparative matrix view of recombinase activities Alliance human TPO gene page

Disease models

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(TPO-cre)1Shk

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92293 Kusakabe T, et al., Thyrocyte-specific expression of Cre recombinase in transgenic mice. Genesis. 2004 Jul;39(3):212-6
• All: 48 reference(s)