Tg(tetO-Aurkb,lacZ)41Kra
Transgene Detail
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Symbol: |
Tg(tetO-Aurkb,lacZ)41Kra |
Name: |
transgene insertion 41, Katya Ravid |
MGI ID: |
MGI:3656025 |
Synonyms: |
CMV-Aurora-B/beta-gal, teto-AIM-1 |
Transgene: |
Tg(tetO-Aurkb,lacZ)41Kra Location: unknown
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Alliance: |
Tg(tetO-Aurkb,lacZ)41Kra page
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Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence, Reporter) |
Inducer: |
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doxycycline/tetracycline |
Mutation: |
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Insertion
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Mutation details: A vector pBI-G (Clontech #6150-1) was used to create this transgene. The vector contains a prokaryotic beta-galactosidase (lacZ) reporter gene under the control of the tetracycline-response element (TRE; containing seven direct repeats of the tetracycline operator (tetO) sequence fused to bidirectional cytomegalovirus (CMV) minimal promoter). The rat Aurora-kinase B cDNA (with N-terminal FLAG-tag sequence and 3' linked beta-globin gene) was placed downstream of the promoter and the purified construct was injected into fertilized FVB/NJ eggs to create the transgenic mice.
(J:104239)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:104239 Nguyen HG, et al., Conditional overexpression of transgenes in megakaryocytes and platelets in vivo. Blood. 2005 Sep 1;106(5):1559-64 |
All: |
1 reference(s) |
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