Tg(H2-K-Cd86)7All
Transgene Detail

Summary

• Symbol: Tg(H2-K-Cd86)7All
• Name: transgene insertion 7, James P Allison
• MGI ID: MGI:3656399
• Synonyms: B7.2^hi
• Transgene: Tg(H2-K-Cd86)7All Location: unknown
• Alliance: Tg(H2-K-Cd86)7All page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(H2-K-Cd86)7All expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cd86 (MGI:101773)

• Mutation details: A construct in which Cd86 cDNA containing the coding region was placed under control of the H2-K^b promoter and immunoglobulin heavy chain enhancer was used to create the transgene. Line 7 showed high levels of Cd86 expression on B lymphocytes. (J:112475)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:112475 Fournier S, et al., T cell-mediated elimination of B7.2 transgenic B cells. Immunity. 1997 Mar;6(3):327-39
• All: 4 reference(s)