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Tg(Lck-Cxadr)1Jdgr
Transgene Detail
Summary
Symbol: Tg(Lck-Cxadr)1Jdgr
Name: transgene insertion 1, James DeGregori
MGI ID: MGI:3686860
Synonyms: CARdelta1 Tg, CAR Tg
Transgene: Tg(Lck-Cxadr)1Jdgr  Location: unknown  
Alliance: Tg(Lck-Cxadr)1Jdgr page
Transgene
origin
Strain of Origin:  FVB/NJ
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Lck-Cxadr)1Jdgr expresses 1 gene
 
Mutation detailsA cDNA encoding the coxsackie/adenovirus receptor (CAR) protein, but lacking the cytoplasmic domain was cloned into a construct containing the LckB proximal promoter/human CD2 enhancer. (J:109884)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:109884 Wan YY, et al., Transgenic expression of the coxsackie/adenovirus receptor enables adenoviral-mediated gene delivery in naive T cells. Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13784-9
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory