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Mfap1b Gene Detail
Summary
  • Symbol
    Mfap1b
  • Name
    microfibrillar-associated protein 1B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3694697
    NCBI Gene: 100034361
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:121292147-121304504 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 60.40 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3694697
 protein coding gene Chr2:121290716-121304548 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026397
 protein coding gene Chr2:124365728-124389592 (-)
A/J MGP_AJ_G0026357
 protein coding gene Chr2:119316977-119347204 (-)
AKR/J MGP_AKRJ_G0026336
 protein coding gene Chr2:122625457-122650052 (-)
BALB/cJ MGP_BALBcJ_G0026370
 protein coding gene Chr2:119508719-119521013 (-)
C3H/HeJ MGP_C3HHeJ_G0026116
 protein coding gene Chr2:123105736-123130402 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026818
 protein coding gene Chr2:128469394-128483767 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026094
 protein coding gene Chr2:132956950-132978102 (-)
DBA/2J MGP_DBA2J_G0026231
 protein coding gene Chr2:118729179-118749706 (-)
FVB/NJ MGP_FVBNJ_G0026193
 protein coding gene Chr2:117510493-117524836 (-)
LP/J MGP_LPJ_G0026332
 protein coding gene Chr2:124627708-124684371 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026213
 protein coding gene Chr2:137188472-137200470 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026873
 protein coding gene Chr2:122788757-122808821 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025113
 protein coding gene Chr2:121942378-121954672 (-)
WSB/EiJ MGP_WSBEiJ_G0025647
 protein coding gene Chr2:123639222-123653867 (-)



Homology
more
  • Human Ortholog
    MFAP1, microfibril associated protein 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MFAP1, microfibril associated protein 1
  • Synonyms
    AMP
  • Links
    NCBI Gene ID: 4236
    neXtProt AC: NX_P55081
    UniProt: P55081

  • Chr Location
    15q15.3; chr15:43804492-43824690 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Gene trapped
    3
  • Radiation induced
    1
  • Genomic Mutations
    2 involving Mfap1b
  • Find Mice (IMSR)
    6 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    22
  • cDNA Data
    113
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100034361 NCBI Gene Model | MGI Sequence Detail 12358 C57BL/6J ±  kb
transcript NM_001081975 RefSeq | MGI Sequence Detail 1887 C57BL/6  
polypeptide C0HKD9 UniProt | EBI | MGI Sequence Detail 439 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 115
    Genomic 1
    cDNA 114

    Microarray probesets 1
References
more
  • Summaries
    All 22
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory