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Ifi213 Gene Detail
Summary
  • Symbol
    Ifi213
  • Name
    interferon activated gene 213
  • Synonyms
    E030037K03Rik, Pydc4, Pyr-A
  • Feature Type
    protein coding gene
  • IDs
    MGI:3695276
    NCBI Gene: 623121
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173393849-173426840 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 80.49 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1423 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3695276
protein coding gene Chr1:173393849-173426868 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0016788
protein coding gene Chr1:172063416-172078123 (-)
AKR/J MGP_AKRJ_G0016754
protein coding gene Chr1:177444844-177453267 (-)
BALB/cJ MGP_BALBcJ_G0016749
protein coding gene Chr1:172898566-172905761 (+)
C3H/HeJ MGP_C3HHeJ_G0016573
protein coding gene Chr1:178161737-178168225 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0014918
protein coding gene Chr1:163929132-163937235 (-)
CAST/EiJ MGP_CASTEiJ_G0016154
protein coding gene Chr1:177284916-177492106 (+)
CBA/J MGP_CBAJ_G0016547
protein coding gene Chr1:192006553-192142422 (-)
DBA/2J MGP_DBA2J_G0016654
protein coding gene Chr1:171199195-171206776 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016726
protein coding gene Chr1:180623942-180628821 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016678
protein coding gene Chr1:199225392-199251871 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0015940
protein coding gene Chr1:170394053-170401114 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015724
protein coding gene Chr1:176429750-176436285 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073491 Ensembl Gene Model | MGI Sequence Detail 32992 C57BL/6J ±  kb
transcript ENSMUST00000150649 Ensembl | MGI Sequence Detail 2748 Not Applicable  
polypeptide ENSMUSP00000117222 Ensembl | MGI Sequence Detail 586 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 4
References
more
  • Summaries
    All 22
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:190914 Brunette RL, et al., Extensive evolutionary and functional diversity among mammalian AIM2-like receptors. J Exp Med. 2012 Oct 22;209(11):1969-83
  • Latest
    J:329937 Maltbaek JH, et al., ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP. Immunity. 2022 Oct 11;55(10):1799-1812.e4

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory