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cpfl7 Gene Detail
Summary
  • Symbol
    cpfl7
  • Name
    cone photoreceptor function loss 7
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:3696947
  • Alliance
    gene page
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 19, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutant mice exhibit retinal segment degneration and retinal ganglion cell disruption. Retinal cones have a reduced b-wave dark adapted ERG response. Mutant mice show a high stepping gait and clasp legs when lifted by the tail.
References
more
  • Summaries
    All 2
    Phenotypes 2
  • Earliest
    J:167199 Hawes NL, et al., A New Mouse Model of Cone Photoreceptor Fuction Loss (cpfl7). Invest Ophthalmol Vis Sci. 2007;48(13):1350
  • Latest
    J:166679 Won J, et al., Mouse model resources for vision research. J Ophthalmol. 2011;2011:391384
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory