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Fam174b Gene Detail
Summary
  • Symbol
    Fam174b
  • Name
    family with sequence similarity 174, member B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3698178
    NCBI Gene: 100038347
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:73390055-73426667 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 42.24 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1177 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3698178
 protein coding gene Chr7:73390050-73426667 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032370
 protein coding gene Chr7:75319194-75360039 (+)
A/J MGP_AJ_G0032349
 protein coding gene Chr7:73617737-73655253 (+)
AKR/J MGP_AKRJ_G0032285
 protein coding gene Chr7:75166675-75212511 (+)
BALB/cJ MGP_BALBcJ_G0032361
 protein coding gene Chr7:73368410-73404234 (+)
C3H/HeJ MGP_C3HHeJ_G0032074
 protein coding gene Chr7:75931250-75968278 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032853
 protein coding gene Chr7:78421864-78461735 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029861
 protein coding gene Chr7:76252683-76290834 (+)
CAST/EiJ MGP_CASTEiJ_G0031402
 protein coding gene Chr7:66757838-66802368 (+)
CBA/J MGP_CBAJ_G0032040
 protein coding gene Chr7:80986601-81024022 (+)
DBA/2J MGP_DBA2J_G0032195
 protein coding gene Chr7:72282462-72317976 (+)
FVB/NJ MGP_FVBNJ_G0032150
 protein coding gene Chr7:72334694-72370366 (+)
LP/J MGP_LPJ_G0032276
 protein coding gene Chr7:76540435-76577388 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032187
 protein coding gene Chr7:81137046-81175161 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032871
 protein coding gene Chr7:74633038-74672782 (+)
PWK/PhJ MGP_PWKPhJ_G0031122
 protein coding gene Chr7:65443324-65483431 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030963
 protein coding gene Chr7:61714474-61755895 (+)
WSB/EiJ MGP_WSBEiJ_G0031520
 protein coding gene Chr7:74985156-75022112 (+)



Homology
more
  • Human Ortholog
    FAM174B, family with sequence similarity 174 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM174B, family with sequence similarity 174 member B
  • Links
    NCBI Gene ID: 400451
    neXtProt AC: NX_Q3ZCQ3
    UniProt: Q3ZCQ3

  • Chr Location
    15q26.1; chr15:92617448-92809884 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Genomic Mutations
    3 involving Fam174b
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    5 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    834
  • Tissues
    17
  • cDNA Data
    5
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100038347 NCBI Gene Model | MGI Sequence Detail 36613 C57BL/6J ±  kb
transcript NM_001162532 RefSeq | MGI Sequence Detail 2678 C57BL/6  
polypeptide Q8K064 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory