Gm10146 Pseudogene Detail

Summary

• Symbol
  Gm10146
• Name
  predicted gene 10146

• Feature Type
  pseudogene
• IDs
  MGI:3704367
  NCBI Gene: 100041500
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr10:78229154-78229462 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 39.72 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  89 from dbSNP Build 142
• Strain Annotations
  8

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3704367	pseudogene	Chr10:78229138-78229590 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0036055	protein coding gene	ChrX:130876198-130876388 (-)
A/J	MGP_AJ_G0025288	protein coding gene	Chr2:504457-504807 (+)
AKR/J	no annotation
BALB/cJ	MGP_BALBcJ_G0025284	protein coding gene	Chr2:489943-490284 (+)
C3H/HeJ	MGP_C3HHeJ_G0025044	protein coding gene	Chr2:531022-531372 (+)
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	MGP_DBA2J_G0025155	protein coding gene	Chr2:482467-489535 (+)
FVB/NJ	MGP_FVBNJ_G0025117	protein coding gene	Chr2:495646-496033 (+)
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	MGP_PWKPhJ_G0024257	protein coding gene	Chr2:481909-489179 (+)
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Gm10146
  

Human Diseases

• References
  2 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  28 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Targeted
  3
• Genomic Mutations
  4 involving Gm10146
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  12
• RefSeq
  1

• Ensembl
  ENSMUSG00000064317 (Evidence)
• NCBI Gene
  100041500

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000064317	Ensembl Gene Model | MGI Sequence Detail	309	C57BL/6J
transcript	ENSMUST00000072739	Ensembl | MGI Sequence Detail	309	Not Applicable

References

• Summaries
  All 32

  Diseases 2

  Phenotypes 28
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:351211 Wu Y, et al., Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathol Commun. 2023 Aug 14;11(1):132

TSS for Gm10146:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr94326	Chr10:78229132-78229142 (+)	-17 bp