Sicd1 QTL Detail

Summary

• Symbol
  Sicd1
• Name
  seizure-induced cell death 1

• Feature Type
  QTL
• IDs
  MGI:3706135
  NCBI Gene: 100038806
• Candidate Genes
  1 Gene

Location &
Maps

• Sequence Map
  Chr18:80175264-89590914 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 18, 53.28 cM (cM position of peak correlated region/marker)
• Mapping Data
  3 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 2 alleles in 4 genetic backgrounds
  3 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

Sequences &
Gene Models

• NCBI Gene
  100038806

References

• Summaries
  All 6

  Phenotypes 3
• Earliest
  J:119634 Schauwecker PE, et al., Genetic control of sensitivity to hippocampal cell death induced by kainic acid: a quantitative trait loci analysis. J Comp Neurol. 2004 Sep 6;477(1):96-107
• Latest
  J:150102 Kong S, et al., Variation in Galr1 expression determines susceptibility to exocitotoxin-induced cell death in mice. Genes Brain Behav. 2008 Jul;7(5):587-98

Candidate Genes for Sicd1:

Gene	Genome Location (GRCm39)	Reference	QTL Note
Galr1	Chr18:82410621-82424902 (-)	J:150102	Candidate loci within the Sicd1 QTL region were identified from the 79 Mb to 84 Mb. Galr1 was indicated as a promising candidate, but more analysis needed to be done.