Tg(Alb-F5)3Dgi
Transgene Detail
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Symbol: |
Tg(Alb-F5)3Dgi |
Name: |
transgene insertion 3, David Ginsburg |
MGI ID: |
MGI:3709370 |
Synonyms: |
AlbB |
Transgene: |
Tg(Alb-F5)3Dgi Location: unknown
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Alliance: |
Tg(Alb-F5)3Dgi page
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Strain of Origin: |
(C57BL/6 x SJL)F1 or C57BL/6 x (C57BL/6 x SJL)F1
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Alb-F5)3Dgi expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
F5 (MGI:88382) |
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Mutation details: The transgenic construct has the mouse albumin promoter driving expression of the murine F5 (FV) gene including the entire coding sequence. An IRES-EGFP cassette with a bacterial gene wasinserting after the F5 coding sequence. A chimeric intron with optimized splice signals was introduced upstream of the F5 cDNA enhance gene expression. Transgenic F5 expression is restricted to the liver. EGFP expression is not detected.
(J:86150)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:86150 Sun H, et al., The murine platelet and plasma factor V pools are biosynthetically distinct and sufficient for minimal hemostasis. Blood. 2003 Oct 15;102(8):2856-61 |
All: |
2 reference(s) |
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