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Ccl27al Gene Detail
Summary
  • Symbol
    Ccl27al
  • Name
    C-C motif chemokine ligand 27A like
  • Synonyms
    Gm13306
  • Feature Type
    protein coding gene
  • IDs
    MGI:3713752
    NCBI Gene: 100039863
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:42153436-42158839 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 22.29 cM
Strain
Comparison
more
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3713752
 protein coding gene Chr4:42153404-42158846 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028177
 protein coding gene Chr4:39736651-39737398 (-)
A/J MGP_AJ_G0028136
 protein coding gene Chr4:38226475-38236901 (-)
AKR/J MGP_AKRJ_G0028097
 protein coding gene Chr4:39232112-39232859 (-)
BALB/cJ MGP_BALBcJ_G0028148
 protein coding gene Chr4:38569218-38576659 (-)
C3H/HeJ MGP_C3HHeJ_G0027870
 protein coding gene Chr4:39699003-39708580 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028588
 protein coding gene Chr4:41237539-41238286 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0027847
 protein coding gene Chr4:42604250-42608930 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0027958
 protein coding gene Chr4:37474247-37474994 (-)
LP/J MGP_LPJ_G0028099
 protein coding gene Chr4:39829944-39830691 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0027050
 protein coding gene Chr4:38195730-38210069 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCL27, C-C motif chemokine ligand 27
  • Synonyms
    ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
  • Links
    NCBI Gene ID: 10850
    neXtProt AC: NX_Q9Y4X3
    UniProt: Q9Y4X3

  • Chr Location
    9p13.3; chr9:34661880-34664048 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from multigenic genotypes
    6 phenotype references
  • All Mutations and Alleles
    5
  • Chemically and radiation induced
    1
  • Endonuclease-mediated
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Ccl27al
  • Find Mice (IMSR)
    4 strains or lines available
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    818
  • Tissues
    16
  • cDNA Data
    3
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073877 Ensembl Gene Model | MGI Sequence Detail 5404 C57BL/6J ±  kb
transcript ENSMUST00000108018 Ensembl | MGI Sequence Detail 542 Not Applicable  
polypeptide ENSMUSP00000103653 Ensembl | MGI Sequence Detail 135 Not Applicable  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
Other
Accession IDs
less
MGI:7526409
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:55764 Hromas R, et al., Isolation of ALP, a novel divergent murine CC chemokine with a unique carboxy terminal extension. Biochem Biophys Res Commun. 1999 May 19;258(3):737-40
  • Latest
    J:330550 Davila ML, et al., CCL27 is a crucial regulator of immune homeostasis of the skin and mucosal tissues. iScience. 2022 Jun 17;25(6):104426
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory