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Cyp3a41b Gene Detail
Summary
  • Symbol
    Cyp3a41b
  • Name
    cytochrome P450, family 3, subfamily a, polypeptide 41B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3714859
    NCBI Gene: 100041375
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:145495474-145521540 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 85.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    289 from dbSNP Build 142
  • Strain Annotations
    8
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3714859
 protein coding gene Chr5:145495474-145521542 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030370
 protein coding gene Chr5:151307646-151351610 (-)
A/J MGP_AJ_G0030336
 protein coding gene Chr5:144397625-144910589 (-)
AKR/J MGP_AKRJ_G0030269
 protein coding gene Chr5:148896065-148935561 (-)
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0030800
 protein coding gene Chr5:156908321-156935123 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0030036
 protein coding gene Chr5:163233059-163317941 (-)
DBA/2J MGP_DBA2J_G0030186
 protein coding gene Chr5:144436138-144489580 (-)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0030171
 protein coding gene Chr5:165161224-165239623 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYP3A5, cytochrome P450 family 3 subfamily A member 5
  • Synonyms
    CP35, CYPIIIA5, P450PCN3, PCN3
  • Links
    NCBI Gene ID: 1577
    neXtProt AC: NX_P20815
    UniProt: P20815

  • Chr Location
    7q22.1; chr7:99648194-99679996 (-)  GRCh38
Human Diseases
more
  • Diseases
    5 with human CYP3A4,CYP3A5 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000075552 Ensembl Gene Model | MGI Sequence Detail 26067 C57BL/6J ±  kb
transcript ENSMUST00000075837 Ensembl | MGI Sequence Detail 2064 Not Applicable  
polypeptide ENSMUSP00000075234 Ensembl | MGI Sequence Detail 504 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 16
References
more
  • Summaries
    All 36
    Gene Ontology 3
    Phenotypes 23
  • Earliest
    J:61903 Sakuma T, et al., A novel female-specific member of the CYP3A gene subfamily in the mouse liver. Arch Biochem Biophys. 2000 May 1;377(1):153-62
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory