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Mir208b Gene Detail
Summary
  • Symbol
    Mir208b
  • Name
    microRNA 208b
  • Synonyms
    Mirn208b, mmu-mir-208b
  • Feature Type
    miRNA gene
  • IDs
    MGI:3718461
    NCBI Gene: 100124433
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55213157-55213233 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3718461
 miRNA gene Chr14:55213157-55213233 (-)
129S1/SvImJ MGP_129S1SvImJ_G0008123
 miRNA gene Chr14:48962575-48962651 (-)
A/J MGP_AJ_G0008110
 miRNA gene Chr14:47994812-47994888 (-)
AKR/J MGP_AKRJ_G0008088
 miRNA gene Chr14:49718614-49718690 (-)
BALB/cJ MGP_BALBcJ_G0008092
 miRNA gene Chr14:47971495-47971571 (-)
C3H/HeJ MGP_C3HHeJ_G0008036
 miRNA gene Chr14:49434697-49434773 (-)
C57BL/6NJ MGP_C57BL6NJ_G0008282
 miRNA gene Chr14:51435603-51435679 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0007373
 miRNA gene Chr14:46406647-46406723 (-)
CAST/EiJ MGP_CASTEiJ_G0007914
 miRNA gene Chr14:45675194-45675270 (-)
CBA/J MGP_CBAJ_G0008004
 miRNA gene Chr14:52996355-52996431 (-)
DBA/2J MGP_DBA2J_G0008040
 miRNA gene Chr14:47735595-47735671 (-)
FVB/NJ MGP_FVBNJ_G0008063
 miRNA gene Chr14:47200719-47200795 (-)
LP/J MGP_LPJ_G0008123
 miRNA gene Chr14:50049215-50049291 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0008032
 miRNA gene Chr14:52378291-52378367 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0008278
 miRNA gene Chr14:48925926-48926002 (-)
PWK/PhJ MGP_PWKPhJ_G0007836
 miRNA gene Chr14:44273709-44273785 (-)
SPRET/EiJ MGP_SPRETEiJ_G0007731
 miRNA gene Chr14:44906109-44906185 (-)
WSB/EiJ MGP_WSBEiJ_G0007991
 miRNA gene Chr14:49217995-49218071 (-)



Homology
more
  • Human Ortholog
    MIR208B, microRNA 208b
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR208B, microRNA 208b
  • Synonyms
    mir-208b, MIRN208B
  • Links
    NCBI Gene ID: 100126336

  • Chr Location
    chr14:23417987-23418063 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Mir208b
  • Find Mice (IMSR)
    0 strains or lines available
Mice homozygous for a knock-out allele exhibit no overt abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    9
  • Literature Summary
    5
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124433 NCBI Gene Model | MGI Sequence Detail 77 C57BL/6J ±  kb
transcript NR_030607 RefSeq | MGI Sequence Detail 77 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 3
    Other 3
Other Database
Links
less
miRBase MI0005552
References
more
  • Summaries
    All 17
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:321964 Li X, et al., MiR-208b Regulates the Conversion of Skeletal Muscle Fiber Types by Inhibiting Mettl8 Expression. Front Genet. 2022;13:820464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory