About   Help   FAQ
Mir453 Gene Detail
Summary
  • Symbol
    Mir453
  • Name
    microRNA 453
  • Synonyms
    Mirn453, mmu-mir-453
Location &
Maps
more
  • Sequence Map
    Chr12:109702053-109702134 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3718517
 miRNA gene Chr12:109702053-109702134 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008012
 miRNA gene Chr12:111979265-111979346 (+)
A/J MGP_AJ_G0008006
 miRNA gene Chr12:107661501-107661582 (+)
AKR/J MGP_AKRJ_G0007983
 miRNA gene Chr12:110798981-110799062 (+)
BALB/cJ MGP_BALBcJ_G0007985
 miRNA gene Chr12:108132287-108132368 (+)
C3H/HeJ MGP_C3HHeJ_G0007931
 miRNA gene Chr12:111242173-111242254 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008166
 miRNA gene Chr12:115389924-115390005 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007293
 miRNA gene Chr12:104181569-104181650 (+)
CAST/EiJ MGP_CASTEiJ_G0007819
 miRNA gene Chr12:106201834-106201915 (+)
CBA/J MGP_CBAJ_G0007901
 miRNA gene Chr12:119924923-119925004 (+)
DBA/2J MGP_DBA2J_G0007936
 miRNA gene Chr12:107216134-107216215 (+)
FVB/NJ MGP_FVBNJ_G0007955
 miRNA gene Chr12:106010114-106010195 (+)
LP/J MGP_LPJ_G0008017
 miRNA gene Chr12:111802187-111802268 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007926
 miRNA gene Chr12:123086626-123086707 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008161
 miRNA gene Chr12:110282366-110282447 (+)
PWK/PhJ MGP_PWKPhJ_G0007741
 miRNA gene Chr12:101826819-101826900 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007638
 miRNA gene Chr12:104446989-104447070 (+)
WSB/EiJ MGP_WSBEiJ_G0007888
 miRNA gene Chr12:111197955-111198036 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    1
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    22
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124484 NCBI Gene Model | MGI Sequence Detail 82 C57BL/6J ±  kb
transcript NR_030559 RefSeq | MGI Sequence Detail 82 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 1
    Other 1
Other Database
Links
less
miRBase MI0005497
References
more
  • Summaries
    All 12
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:283772 Liko D, et al., Loss of TSC complex enhances gluconeogenesis via upregulation of Dlk1-Dio3 locus miRNAs. Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1524-1532
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory