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Mir511 Gene Detail
Summary
  • Symbol
    Mir511
  • Name
    microRNA 511
  • Synonyms
    Mirn511, mmu-mir-511
Location &
Maps
more
  • Sequence Map
    Chr2:14265814-14265892 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 10.48 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    163 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3718546
 miRNA gene Chr2:14265814-14265892 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008505
 miRNA gene Chr2:11775784-11775862 (+)
A/J MGP_AJ_G0008493
 miRNA gene Chr2:11342232-11342310 (+)
AKR/J MGP_AKRJ_G0008478
 miRNA gene Chr2:11677068-11677146 (+)
BALB/cJ MGP_BALBcJ_G0008482
 miRNA gene Chr2:11338457-11338535 (+)
C3H/HeJ MGP_C3HHeJ_G0008421
 miRNA gene Chr2:11616374-11616452 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008688
 miRNA gene Chr2:12092200-12092278 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007677
 miRNA gene Chr2:10891453-10891531 (+)
CAST/EiJ MGP_CASTEiJ_G0008279
 miRNA gene Chr2:11595979-11596057 (+)
CBA/J MGP_CBAJ_G0008386
 miRNA gene Chr2:12622858-12622936 (+)
DBA/2J MGP_DBA2J_G0008424
 miRNA gene Chr2:11249482-11249560 (+)
FVB/NJ MGP_FVBNJ_G0008442
 miRNA gene Chr2:11130716-11130794 (+)
LP/J MGP_LPJ_G0008512
 miRNA gene Chr2:11701064-11701142 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008404
 miRNA gene Chr2:12445701-12445779 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008677
 miRNA gene Chr2:11582812-11582890 (+)
PWK/PhJ MGP_PWKPhJ_G0008206
 miRNA gene Chr2:11102351-11102429 (+)
SPRET/EiJ MGP_SPRETEiJ_G0008067
 miRNA gene Chr2:11646400-11646478 (+)
WSB/EiJ MGP_WSBEiJ_G0008367
 miRNA gene Chr2:11717549-11717627 (+)



Homology
more
  • Human Ortholog
    MIR511, microRNA 511
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR511, microRNA 511
  • Synonyms
    hsa-mir-511, hsa-mir-511-2, mir-511, MIR511-1, MIR511-2, MIRN511-1, MIRN511-2
  • Links
    NCBI Gene ID: 574445

  • Chr Location
    chr10:17845107-17845193 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show protection from DSS-induced colitis and macrophages show reduced LPS- and Poly I:C-mediated cytokine responses.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    4
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      23
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100124488 NCBI Gene Model | MGI Sequence Detail 79 C57BL/6J ±  kb
    transcript NR_030609 RefSeq | MGI Sequence Detail 79 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 1
      Other 1
    Other Database
    Links
    less
    miRBase MI0005554
    References
    more
    • Summaries
      All 18
      Developmental Gene Expression 3
      Gene Ontology 2
      Phenotypes 3
    • Earliest
      J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
    • Latest
      J:345580 Rahman S, et al., miR-511 Deficiency Protects Mice from Experimental Colitis by Reducing TLR3 and TLR4 Responses via WD Repeat and FYVE-Domain-Containing Protein 1. Cells. 2021 Dec 25;11(1)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory