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Mir582 Gene Detail
Summary
  • Symbol
    Mir582
  • Name
    microRNA 582
  • Synonyms
    Mirn582, mmu-mir-582
Location &
Maps
more
  • Sequence Map
    Chr13:109461278-109461358 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 13, 59.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    129 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3718550
miRNA gene Chr13:109461278-109461358 (+)
129S1/SvImJ MGP_129S1SvImJ_G0008096
miRNA gene Chr13:111676995-111677075 (+)
A/J MGP_AJ_G0008084
miRNA gene Chr13:107260310-107260390 (+)
AKR/J MGP_AKRJ_G0008064
miRNA gene Chr13:110526235-110526315 (+)
BALB/cJ MGP_BALBcJ_G0008066
miRNA gene Chr13:107986438-107986518 (+)
C3H/HeJ MGP_C3HHeJ_G0008010
miRNA gene Chr13:110289812-110289892 (+)
C57BL/6NJ MGP_C57BL6NJ_G0008253
miRNA gene Chr13:115053692-115053772 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0007350
miRNA gene Chr13:102688602-102688682 (+)
CAST/EiJ MGP_CASTEiJ_G0007890
miRNA gene Chr13:109839421-109839501 (+)
CBA/J MGP_CBAJ_G0007978
miRNA gene Chr13:119459216-119459296 (+)
DBA/2J MGP_DBA2J_G0008013
miRNA gene Chr13:107012242-107012322 (+)
FVB/NJ MGP_FVBNJ_G0008037
miRNA gene Chr13:105690577-105690657 (+)
LP/J MGP_LPJ_G0008096
miRNA gene Chr13:111779312-111779392 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0008005
miRNA gene Chr13:119872604-119872684 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0008251
miRNA gene Chr13:109975028-109975108 (+)
PWK/PhJ MGP_PWKPhJ_G0007810
miRNA gene Chr13:105731421-105731501 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007707
miRNA gene Chr13:106237413-106237493 (+)
WSB/EiJ MGP_WSBEiJ_G0007964
miRNA gene Chr13:110547354-110547434 (+)



Homology
more
  • Human Ortholog
    MIR582, microRNA 582
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR582, microRNA 582
  • Synonyms
    hsa-mir-582, MIRN582
  • Links
    NCBI Gene ID: 693167

  • Chr Location
    chr5:59703606-59703703 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice show reduced number of neural stem cells and increased number of neuroblasts in the subventricular zone indicating reduced stemness and enhanced neurogenesis of neural stem cells.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    • All Sequences
    • RefSeq
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 100124489 NCBI Gene Model | MGI Sequence Detail 81 C57BL/6J ±  kb
    transcript NR_030644 RefSeq | MGI Sequence Detail 81 C57BL/6  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 2
      Other 2
    Other Database
    Links
    less
    miRBase MI0006127
    References
    more
    • Summaries
      All 8
      Developmental Gene Expression 2
      Phenotypes 2
    • Earliest
      J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
    • Latest
      J:325358 Zhang YF, et al., MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1. Front Cell Neurosci. 2022;16:866020

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory