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Tg(Ins2-cre)5Lt
Transgene Detail
Summary
Symbol: Tg(Ins2-cre)5Lt
Name: transgene insertion 5, Edward Leiter
MGI ID: MGI:3721303
Synonyms: line 5, RIP-cre, line 5, RIP-cre, line5, RIPCreV
Transgene: Tg(Ins2-cre)5Lt  Location: unknown  
Alliance: Tg(Ins2-cre)5Lt page
Transgene
origin
Strain of Origin:  NOD/ShiLt
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Ins2-cre)5Lt expression driven by 1 gene
 
Mutation detailsA construct with the rat insulin II promoter driving cre recombinase was injected into fertilized NOD/ShiLt embryos. Line 3 was established by mating to NOD/ShiLt mice prior to sibling mating. Mice overexpress Cre specifically in pancreatic beta cells. (J:124298)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ins2 (rat)
Summary of all recombinase alleles driven by Ins2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:124298 Leiter E, Generation of pancreatic beta-cell specific cre transgenic mice line 5. MGI Direct Data Submission. 2007;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory