Tg(HSA*LR)32bCath
Transgene Detail

Summary

• Symbol: Tg(HSA*LR)32bCath
• Name: transgene insertion 32b, Charles A Thornton
• MGI ID: MGI:3763910
• Synonyms: LR32b, Tg(HSA*LR)32b
• Transgene: Tg(HSA*LR)32bCath Location: unknown
• Alliance: Tg(HSA*LR)32bCath page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(HSA*LR)32bCath expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACTA1 (58)

  Acta1

  (MGI:87902)

• Mutation details: The transgene contains human HSA with an expanded (250 repeats) CTG inserted into the last exon. Seven lines were created with expression restricted to skeletal muscle. This line contains 2 transgene insertions. (J:64493)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:64493 Mankodi A, et al., Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat [see comments]. Science. 2000 Sep 8;289(5485):1769-73
• All: 1 reference(s)