Aec2 QTL Detail

Summary

• Symbol
  Aec2
• Name
  autoimmune exocrinopathy 2

• Feature Type
  QTL
• IDs
  MGI:3769155

Location &
Maps

• Sequence Map
  Chr1:52457737-182250592 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  3 experiments

Human Diseases

• Mutations/Alleles
  1 with disease annotations

• References
  3 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotypes from multigenic genotypes
  13 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 14

  Diseases 3

  Phenotypes 13
• Earliest
  J:128900 Cha S, et al., Two NOD Idd-associated intervals contribute synergistically to the development of autoimmune exocrinopathy (Sjogren's syndrome) on a healthy murine background. Arthritis Rheum. 2002 May;46(5):1390-8
• Latest
  J:357178 Peck AB, et al., A Temporal Comparative RNA Transcriptome Profile of the Annexin Gene Family in the Salivary versus Lacrimal Glands of the Sjogren's Syndrome-Susceptible C57BL/6.NOD-Aec1Aec2 Mouse. Int J Mol Sci. 2022 Oct 3;23(19)