Del(7Herc2-Mkrn3)13FRdni Cytogenetic Marker Detail

Summary

• Symbol
  Del(7Herc2-Mkrn3)13FRdni
• Name
  deletion, Chr 7, R D Nicholls13F
• Synonyms
  Del13FRdni, Tg^PWS/AS(del)

• Feature Type
  chromosomal deletion
• IDs
  MGI:3769761

Location &
Maps

• Sequence Map
  Chr7:55699944-62069887 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 7, Syntenic

Human Diseases

• Diseases
  1 with Del(7Herc2-Mkrn3)13FRdni mouse models

Human Disease

Mouse Models

Prader-Willi syndrome

IDs

Prader-Willi syndrome      

DOID:11983
ICD10CM:Q87.11
ICD9CM:759.81
MESH:D011218
NCI:C75463
OMIM:176270
ORDO:739
UMLS_CUI:C0032897

View 1 model

Mouse Models

Human Disease Modeled: Prader-Willi syndrome

Allelic Composition	Genetic Background	Reference	Phenotypes
Del(7Herc2-Mkrn3)13FRdni/+	involves: C57BL/6 * CD-1 * SJL	J:56614	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotypes from 1 allele in 1 genetic background
  7 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 8

  Diseases 1

  Phenotypes 7
• Earliest
  J:56614 Gabriel JM, et al., A transgene insertion creating a heritable chromosome deletion mouse model of Prader-Willi and angelman syndromes. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9258-63
• Latest
  J:198496 Resnick JL, et al., Recommendations for the investigation of animal models of Prader-Willi syndrome. Mamm Genome. 2013 Jun;24(5-6):165-78