Cbll Gene Detail

Summary

• Symbol
  Cbll
• Name
  cerebelless

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:3771554
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  12 phenotypes from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for an intergenic deletion caused by random insertion of a transgene exhibit decreased body size, tremors, ataxia, impaired coordination, absent cerebellar cortex, failure of GABAergic neuron production, and loss of external germinal layer, pontine and olivary nuclei.

References

• Summaries
  All 4

  Phenotypes 4
• Earliest
  J:100997 Hoshino M, et al., Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron. 2005 Jul 21;47(2):201-13
• Latest
  J:210443 Yamada M, et al., Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons. J Neurosci. 2014 Apr 2;34(14):4786-800