Mfsd4b3-ps Pseudogene Detail

Summary

• Symbol
  Mfsd4b3-ps
• Name
  major facilitator superfamily domain containing 4B3, pseudogene
• Synonyms
  G630090E17Rik, Mfsd4b3

• Feature Type
  pseudogene
• IDs
  MGI:3773841
  NCBI Gene: 100041085
• Alliance
  gene page
• Transcription Start Sites
  4 TSS

Location &
Maps

• Sequence Map
  Chr10:39822919-39836086 bp, - strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 21.35 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  457 from dbSNP Build 142
• Strain Annotations
  15

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3773841	pseudogene	Chr10:39822903-39836149 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0017156	protein coding gene	Chr10:38486671-38501516 (-)
A/J	MGP_AJ_G0017133	protein coding gene	Chr10:37449846-37462996 (-)
AKR/J	MGP_AKRJ_G0017093	protein coding gene	Chr10:37975631-37990067 (-)
BALB/cJ	MGP_BALBcJ_G0017096	protein coding gene	Chr10:37515782-37530267 (-)
C3H/HeJ	MGP_C3HHeJ_G0016916	protein coding gene	Chr10:38299438-38315624 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017554	protein coding gene	Chr10:39660060-39676635 (-)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0016495	protein coding gene	Chr10:38477855-38489890 (-)
CBA/J	MGP_CBAJ_G0016890	protein coding gene	Chr10:41490806-41505788 (-)
DBA/2J	MGP_DBA2J_G0016995	protein coding gene	Chr10:36969129-36982006 (-)
FVB/NJ	MGP_FVBNJ_G0016990	protein coding gene	Chr10:36470886-36488531 (-)
LP/J	MGP_LPJ_G0017072	protein coding gene	Chr10:38450642-38467265 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017020	protein coding gene	Chr10:42330273-42346364 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017591	protein coding gene	Chr10:37964048-37980110 (-)
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0016558	protein coding gene	Chr10:38239007-38260817 (-)

Homology

• Human Ortholog
  MFSD4B, major facilitator superfamily domain containing 4B

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  MFSD4B, major facilitator superfamily domain containing 4B
  
• Synonyms
  KIAA1919, NaGLT1, SLC60A2
• Links
  HGNC:21053

  NCBI Gene ID: 91749

  neXtProt AC: NX_Q5TF39

  UniProt: Q5TF39

  
  
• Chr Location
  6q21; chr6:111259327-111445354 (+)  GRCh38

---

• MGI Vertebrate Homology
  Mfsd4b3-ps stringent orthology
  1 human;1 mouse;1 zebrafish
  
• HCOP
  vertebrate homology predictions: MFSD4B
• Gene Tree
  Mfsd4b3-ps
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Targeted
  1
• Genomic Mutations
  2 involving Mfsd4b3-ps
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  10 strains or lines available

Expression

• Assay Results
  706
• cDNA Data
  2

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  21
• RefSeq
  1
• CCDS
  CCDS48540.1

• Ensembl
  ENSMUSG00000071335 (Evidence)
• NCBI Gene
  100041085

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000071335	Ensembl Gene Model | MGI Sequence Detail	13168	C57BL/6J
transcript	ENSMUST00000239163	Ensembl | MGI Sequence Detail	1708	Not Applicable

Molecular
Reagents

• All nucleic 2

  cDNA 2

  
  

  Microarray probesets 2

Other
Accession IDs

MGI:3781307, MGI:6280697

References

• Summaries
  All 19

  Phenotypes 7
• Earliest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
• Latest
  J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

TSS for Mfsd4b3-ps:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr97351	Chr10:39836239-39836279 (-)	-173 bp
Tssr97350	Chr10:39836191-39836229 (-)	-124 bp
Tssr97349	Chr10:39836168-39836183 (-)	-90 bp
Tssr97348	Chr10:39836140-39836158 (-)	-63 bp