Tg(Mitf-cre)7114Gsb
Transgene Detail

Summary

• Symbol: Tg(Mitf-cre)7114Gsb
• Name: transgene insertion 7114, Gregory S Barsh
• MGI ID: MGI:3778684
• Synonyms: MitfCre
• Transgene: Tg(Mitf-cre)7114Gsb Location: unknown
• Alliance: Tg(Mitf-cre)7114Gsb page

Transgene origin

• Strain of Origin: (CBA x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mitf-cre)7114Gsb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Mitf (MGI:104554)

• Mutation details: A cre coding region was inserted prior to the protein coding region of Mitf contained within BAC RP23-271N22. 3 lines were created and one line was studied (line 7114). Cre expression under the control of the Mitf promoter was confirmed to be melanocyte-specific. (J:132975)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mitf (mouse) Summary of all recombinase alleles driven by Mitf. Comparative matrix view of recombinase activities Alliance mouse Mitf gene page

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132975 Alizadeh A, et al., Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements. Pigment Cell Melanoma Res. 2008 Feb;21(1):63-9
• All: 7 reference(s)