Pramel58 Gene Detail

Summary

• Symbol
  Pramel58
• Name
  PRAME like 58
• Synonyms
  Gm6205

• Feature Type
  protein coding gene
  BioType Conflict
  
• IDs
  MGI:3779572
  NCBI Gene: 621203
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr5:94830504-94833233 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 47.29 cM
• Mapping Data
  2 experiments

Strain
Comparison

• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_3779572	protein coding gene	Chr5:94796275-94833419 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Human Ortholog
  PRAMEF10, PRAME family member 10

• Vertebrate Orthologs
  9

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  PRAMEF10, PRAME family member 10
  
• Links
  HGNC:27997

  NCBI Gene ID: 343071

  neXtProt AC: NX_O60809

  UniProt: O60809

  
  
• Chr Location
  1p36.21; chr1:12892896-12898270 (-)  GRCh38

---

• Human Ortholog
  PRAMEF12, PRAME family member 12
  
• Links
  HGNC:22125

  NCBI Gene ID: 390999

  neXtProt AC: NX_O95522

  UniProt: O95522

  
  
• Chr Location
  1p36.21; chr1:12773738-12777906 (+)  GRCh38

---

• Human Ortholog
  PRAMEF13, PRAME family member 13
  
• Links
  HGNC:13262

  NCBI Gene ID: 400736

  neXtProt AC: NX_Q5VWM6

  UniProt: Q5VWM6

  
  
• Chr Location
  1p36.21; chr1:13196188-13201409 (-)  GRCh38

---

• Human Ortholog
  PRAMEF18, PRAME family member 18
  
• Links
  HGNC:30693

  NCBI Gene ID: 391003

  neXtProt AC: NX_Q5VWM3

  UniProt: Q5VWM3

  
  
• Chr Location
  1p36.21; chr1:13222695-13226154 (-)  GRCh38

---

• Human Ortholog
  PRAMEF19, PRAME family member 19
  
• Links
  HGNC:24908

  NCBI Gene ID: 645414

  neXtProt AC: NX_Q5SWL8

  UniProt: Q5SWL8

  
  
• Chr Location
  1p36.21; chr1:13368431-13371947 (-)  GRCh38

---

• Human Ortholog
  PRAMEF2, PRAME family member 2
  
• Synonyms
  DJ845O24.3
• Links
  HGNC:28841

  NCBI Gene ID: 65122

  neXtProt AC: NX_O60811

  UniProt: O60811

  
  
• Chr Location
  1p36.21; chr1:12857086-12861909 (+)  GRCh38

---

• Human Ortholog
  PRAMEF33, PRAME family member 33
  
• Synonyms
  PRAMEF33P
• Links
  HGNC:49193

  NCBI Gene ID: 645382

  neXtProt AC: NX_A0A0G2JMD5

  UniProt: A0A0G2JMD5

  
  
• Chr Location
  1p36.21; chr1:13303539-13308907 (+)  GRCh38

---

• Human Ortholog
  PRAMEF7, PRAME family member 7
  
• Links
  HGNC:28415

  NCBI Gene ID: 441871

  neXtProt AC: NX_Q5VXH5

  UniProt: Q5VXH5

  
  
• Chr Location
  1p36.21; chr1:12916610-12920751 (+)  GRCh38

---

• MGI Vertebrate Homology
  Pramel58 stringent orthology
  8 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: PRAMEF10, PRAMEF12, PRAMEF13, PRAMEF18, PRAMEF19, PRAMEF2, PRAMEF33, PRAMEF7
• Gene Tree
  Pramel58
  

Human Diseases

• Diseases
  1 with human PRAME associations

				Human Disease	Mouse Models
				myeloid leukemia IDs myeloid leukemia       DOID:8692 DOID:8878 DOID:8879 DOID:8910 DOID:9066 DOID:9126 ICD10CM:C92 ICD9CM:205 ICD9CM:205.9 MESH:D007951 NCI:C3172 UMLS_CUI:C0023470

Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Radiation induced
  1
• Spontaneous
  1
• Genomic Mutations
  3 involving Pramel58
• Find Mice (IMSR)
  12 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  4

• Ensembl
  ENSMUSG00000092073 (Evidence)
• NCBI Gene
  621203

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000092073	Ensembl Gene Model | MGI Sequence Detail	2730	C57BL/6J
transcript	ENSMUST00000190001	Ensembl | MGI Sequence Detail	1428	Not Applicable

Other
Accession IDs

MGI:3779117, MGI:7466635

References

• Summaries
  All 11

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17